ID B4VMP4_9CYAN Unreviewed; 1210 AA.
AC B4VMP4;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=MC7420_1817 {ECO:0000313|EMBL:EDX76814.1};
OS Coleofasciculus chthonoplastes PCC 7420.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Coleofasciculales;
OC Coleofasciculaceae; Coleofasciculus.
OX NCBI_TaxID=118168 {ECO:0000313|EMBL:EDX76814.1, ECO:0000313|Proteomes:UP000003835};
RN [1] {ECO:0000313|EMBL:EDX76814.1, ECO:0000313|Proteomes:UP000003835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7420 {ECO:0000313|EMBL:EDX76814.1,
RC ECO:0000313|Proteomes:UP000003835};
RA Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS989845; EDX76814.1; -; Genomic_DNA.
DR RefSeq; WP_006099772.1; NZ_DS989845.1.
DR AlphaFoldDB; B4VMP4; -.
DR STRING; 118168.MC7420_1817; -.
DR eggNOG; COG0784; Bacteria.
DR eggNOG; COG3829; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_000445_114_15_3; -.
DR OrthoDB; 415806at2; -.
DR Proteomes; UP000003835; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 4.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 5.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 4.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 5.
DR SMART; SM00091; PAS; 5.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 5.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 4.
DR PROSITE; PS50112; PAS; 4.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000003835}.
FT DOMAIN 54..119
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 262..314
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 315..357
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 390..442
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 475..528
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 550..603
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 604..648
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 657..707
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 725..970
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 996..1112
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 6..33
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 433..478
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1045
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1210 AA; 135304 MW; F9E1A41E90C1EB97 CRC64;
MAEKTREELE QELQDLRDRL SVAEETLQAI RQGEVDALVV SGPAGDQIFT LQSADEPYRL
FVEQMQEGAA TVTSDGMLLY CNRRLADLLQ RNLETVIGSN FKQYLNPVEV PFFQSLLQKD
KAGYSHREFY LIASDQTEIP VELSVSPLMM EGVKVNCLIV TDLTENKRQK KIVAAEKLAR
SIFEQVADAI VVCDQRGTII RTSMATQELC GQNPILQPFD QIFPLMFSSS TIREDNHTIS
SPSPTSGHPF SIATILNGEI FQGIEVVFGR EDGQQFHLLL SGRALLNSKN QIQGCVVTLT
NITARKQSEQ ALQESQERFR RAVLYSPIPI MLHAEDGEVL QINQAWTELT GYTHQDIPTI
ADWTQKAYGT RQGLVQENID QLYHLDQPIG EGEYTIITRN GSTRIWDFSS APLGKLSDGR
RMVISTALDV TLRKQAELEL QQANATLEVR VEERTKALQQ ELQTRHQAEQ ELRASQARFA
GILEIASDGI ISVDANQRII LFNQGAEKMF GYRVSEVLGQ PLDLLLPNRY TIAHHQHIKT
FSHSQGKARR MGERQAIFGR RKDGTEFPAE ASISKLTLGD QVVFTAFVQD ITERKQFEEK
LQQSETRLKT IITATCDGIM IVDRQGQVCF ANPAAAQLFD MTPDALLNYQ WGMPLGETTE
IELMQSSGIG RTAEMKATPI QWFSKSAYVI ALRDITKRKQ ADLSLQQAKA DAEAANQAKS
MFLANMSHEL RTPLNIILGF TQVMSRDPAI TPEEQENLDI INKSGNHLLS LINDVLDLSK
IEAGCISVEE SRFDLIALMR SLQEMFQHKA RAKGLQLHLN IAADVPHYIQ ADSNKLRQVL
INLLSNAIKF TQNGSINLRV ALLKAEGNDH GSDAEDMITP PSSQTRHGTS LQASHLHFEV
SDTGVGIAPT ELGSIFDAFI QTHAGKVANE GTGLGLAISR KFVQLMGGDI QVSSQLNQGS
TFSFEIPVHL ADASDMEPIH THRRVIGLVP NQPCYRIIVT DDKPENRQIL VKLLTFPGLE
VREVENGQEA LTLWQQWQPD LIWMDMRMPI MDGYQATQQI RCQSDSQTPI IIALTAYASK
SDRASALEAG CNDYVTKPFQ VETLFAKMEE YLGVRYVYAD DHPNLSKTTQ LETSVNVNQL
TPECLSVMPL SWIEMLSEAA QLCDDEEIFS LIEQIPPEET LLITTLSHLA HNFQFDPIIQ
LAQSVINSDK
//
