ID B4VVC0_9CYAN Unreviewed; 568 AA.
AC B4VVC0;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=MC7420_4215 {ECO:0000313|EMBL:EDX74230.1};
OS Coleofasciculus chthonoplastes PCC 7420.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Coleofasciculales;
OC Coleofasciculaceae; Coleofasciculus.
OX NCBI_TaxID=118168 {ECO:0000313|EMBL:EDX74230.1, ECO:0000313|Proteomes:UP000003835};
RN [1] {ECO:0000313|EMBL:EDX74230.1, ECO:0000313|Proteomes:UP000003835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7420 {ECO:0000313|EMBL:EDX74230.1,
RC ECO:0000313|Proteomes:UP000003835};
RA Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS989854; EDX74230.1; -; Genomic_DNA.
DR RefSeq; WP_006102535.1; NZ_DS989854.1.
DR AlphaFoldDB; B4VVC0; -.
DR STRING; 118168.MC7420_4215; -.
DR eggNOG; COG0210; Bacteria.
DR HOGENOM; CLU_034823_0_0_3; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000003835; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000003835}.
FT DOMAIN 13..310
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 34..41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 568 AA; 64481 MW; 70B4D326F8A03D2D CRC64;
MLQKLTPSPY QTCILNAVSQ NLILPIKSGI GVIALAGTGK STLITLIAET IQKQGLQPEE
MVILVFGTKN KDDLRKCIQS KLGTKWGRTV RTIHSLAYSI YREALNVSTA NVNPYKYETI
ASKLGWITGN VGRLGRLVAN SDYPAILNEK AFIKLLELLR LYAYQPNPEN IQTLNQTYNL
SVTDFNRVAQ AAKDCLDRGE EEALFRNQID TTDMVWIPWK CQEIPFFKGA IARLKNRLKV
ILIDEAQDVD NLQLSMLQLL ITSSQSFLIA VGDPNQSVYH FRGCLSDGLA KIMSRFNCQV
FESPLNYRCG QLHLQLVRDI FPHIPIQAHP NAPQGEIRII SSADLLKCFT DSTLTYLIVS
RKNSTLIQSA IRIIATGKTA TIKDEKAGDY LFKEIKRIAE KPYNPLTFEH KLDVYAAKTR
HFLEQSPDAP TRLAEFADFI ESIRTLYDTY KPATLQKWQT TINQIFNSRK STSIHLLSIH
SAKGAEAEVV FLLYPEEIPF THSQQSLEEL QQEWNTLYIA LTRIKANRNP GSGILYLVLK
ERDCTIYPDW LPQAYRQLYK FDKPVNSI
//
