ID B4WGZ6_SYNS7 Unreviewed; 606 AA.
AC B4WGZ6;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=S7335_2428 {ECO:0000313|EMBL:EDX84731.1};
OS Synechococcus sp. (strain ATCC 29403 / PCC 7335).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=91464 {ECO:0000313|EMBL:EDX84731.1, ECO:0000313|Proteomes:UP000005766};
RN [1] {ECO:0000313|EMBL:EDX84731.1, ECO:0000313|Proteomes:UP000005766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29403 / PCC 7335 {ECO:0000313|Proteomes:UP000005766};
RA Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; DS989904; EDX84731.1; -; Genomic_DNA.
DR RefSeq; WP_006454478.1; NZ_DS989904.1.
DR AlphaFoldDB; B4WGZ6; -.
DR STRING; 91464.S7335_2428; -.
DR eggNOG; COG3614; Bacteria.
DR eggNOG; COG5002; Bacteria.
DR HOGENOM; CLU_000445_114_39_3; -.
DR OrthoDB; 509491at2; -.
DR Proteomes; UP000005766; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF24; SENSOR HISTIDINE KINASE RPPB; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EDX84731.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005766};
KW Transferase {ECO:0000313|EMBL:EDX84731.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 72..336
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 392..606
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 606 AA; 67216 MW; FDD7B6C40E591D04 CRC64;
MRIGRPTLPI ALTLAVGIGL SGLSAAAIAR QERTNQRLQF QRQTDSLATS LQRSINRYTD
ILLSLSDFYA VAEQTIPRTD FNRFVERALA TYPGIQALEW APFVLADTLN AQGTDSQLTE
IKAENSGLPT RTTFEATIRA EGYPTFQITE QDSQGKLVRA GDRPYYVPVT YVQPYKGNEP
ALGYDLTSDD IRQAALETAR DTGRVAASGR IRLVQEDNNQ FGFLVFLPLY SSRMVPSSVQ
DRRAQLQGYL LGVFRVAEVV EESLETFSYD IDFALSDRSA SPTEELLGVY QANTRTVTTV
FQRNALLTNR KQRTLCPTVE ACVHQLTVGE RSWVIAFTPA ANYPTTTPWR ALSTLIIGLL
LTFMVARYFA QTQSALIKTQ ELSALKIRLF SMASHELRTP LASILLSAQV LETDLDRTER
PRIYRRIRAA AKRMNQLLGD LLTLARAESG KLEFSPETLN LSLFCKQIID EVRCSFDVPP
TVNFIVSSTV PTAAYFDPQL LRAVLTNLLS NAVKYSKELP QVSLSVTCQL HNLVFQVSDR
GIGIHKADQA RLNEAFYRGK NVGHIQGTGL GLSVVSACLQ LHHGTLLCES ALGEGTTFTV
TLPQIE
//
