ID B4WQK5_SYNS7 Unreviewed; 779 AA.
AC B4WQK5;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=exoribonuclease II {ECO:0000256|ARBA:ARBA00012163};
DE EC=3.1.13.1 {ECO:0000256|ARBA:ARBA00012163};
GN ORFNames=S7335_4744 {ECO:0000313|EMBL:EDX87037.1};
OS Synechococcus sp. (strain ATCC 29403 / PCC 7335).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=91464 {ECO:0000313|EMBL:EDX87037.1, ECO:0000313|Proteomes:UP000005766};
RN [1] {ECO:0000313|EMBL:EDX87037.1, ECO:0000313|Proteomes:UP000005766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29403 / PCC 7335 {ECO:0000313|Proteomes:UP000005766};
RA Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to yield
CC nucleoside 5'-phosphates.; EC=3.1.13.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001849};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; DS989904; EDX87037.1; -; Genomic_DNA.
DR RefSeq; WP_006456821.1; NZ_DS989904.1.
DR AlphaFoldDB; B4WQK5; -.
DR STRING; 91464.S7335_4744; -.
DR eggNOG; COG0557; Bacteria.
DR HOGENOM; CLU_002333_7_3_3; -.
DR OrthoDB; 9764149at2; -.
DR Proteomes; UP000005766; Unassembled WGS sequence.
DR GO; GO:0008859; F:exoribonuclease II activity; IEA:UniProtKB-EC.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0016070; P:RNA metabolic process; IEA:InterPro.
DR CDD; cd04471; S1_RNase_R; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 2.
DR InterPro; IPR011129; CSD.
DR InterPro; IPR040476; CSD2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR013223; RNase_B_OB_dom.
DR InterPro; IPR001900; RNase_II/R.
DR InterPro; IPR004476; RNase_II/RNase_R.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00358; 3_prime_RNase; 1.
DR PANTHER; PTHR23355:SF9; DIS3-LIKE EXONUCLEASE 2; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF17876; CSD2; 1.
DR Pfam; PF08206; OB_RNB; 1.
DR Pfam; PF00773; RNB; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00357; CSP; 1.
DR SMART; SM00955; RNB; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000005766}.
FT DOMAIN 681..762
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
SQ SEQUENCE 779 AA; 88138 MW; 67F8D6559AE8FFFC CRC64;
MEFSIASLLA NLSDDKLVAV KTLEKKLNCN TEEAVRDLHI ALTALERTNV LEKSRGKYRK
IENEDVIEGK LRCSSKGFCF AIQDEEGADD IYVRESQLNT AWNGDRVLVQ VTKDGSRRRS
PEGEVKLILE RANESVLAKV KAAETAADKF KAIPLDDRLL FELDIAESEE DLSEAIDHLI
HVEITRYPIA QHPPQGKVSR ILGSDAEDAA DVDIVYCKHD LPRIFSEEVF IAARGLPNRV
RKSDIKGRVD LTEHAALTID GSNAKVIDDA ISLDITDDGY RRLGIHVSDV AHYVQPNDVI
DRTARSRGMA VYLGDEIVPM LPPPIPNALC ALVPDKDRLA ISILITMDDD GQVLEYEIQP
SVIQVSHQLT YDQAQAILVR EEDEELEKLG FSPDDIEEFE PVMDLIDSLY QLSQEVKQRR
HERGSFELNL PQHEFPPEAE ELAEYLSPKF QYDDEGSFGA MVVSDHMPAR IIVTEFMLLA
NQLVARHIKE LGIPGLYRVH RTPELADVQE LVKLANNMEI DLQLEDVEQV APSDYRNFTE
QFKASKSEKV LTYLLLATLK PALYSARPGP HFGLAIDDAY THFASPVRRY PDLLVHRLLH
AVFKHGRDRR STRSKDRVNL RHSSCHGKIN WSVLPPAVQQ EMEEQLTRAP IKLTERERIT
QDAESDLEGL KKAAFMQAHT GEVFHGLITG VQSYGFFVEL EELLVEGLVH VSSLKDDWYE
YRSRQQKLVG RKNRQQYRLG DHVEVEVKSV DYYRQQIDLV AVGGGSEASE EDSELGEEE
//
