ID B4WU25_SYNS7 Unreviewed; 876 AA.
AC B4WU25;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Globin domain protein {ECO:0000313|EMBL:EDX83240.1};
GN ORFNames=S7335_420 {ECO:0000313|EMBL:EDX83240.1};
OS Synechococcus sp. (strain ATCC 29403 / PCC 7335).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=91464 {ECO:0000313|EMBL:EDX83240.1, ECO:0000313|Proteomes:UP000005766};
RN [1] {ECO:0000313|EMBL:EDX83240.1, ECO:0000313|Proteomes:UP000005766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29403 / PCC 7335 {ECO:0000313|Proteomes:UP000005766};
RA Tandeau de Marsac N., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC {ECO:0000256|ARBA:ARBA00005381}.
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DR EMBL; DS989905; EDX83240.1; -; Genomic_DNA.
DR RefSeq; WP_006458143.1; NZ_DS989905.1.
DR AlphaFoldDB; B4WU25; -.
DR STRING; 91464.S7335_420; -.
DR eggNOG; COG1017; Bacteria.
DR eggNOG; COG2114; Bacteria.
DR eggNOG; COG5000; Bacteria.
DR HOGENOM; CLU_015967_0_0_3; -.
DR OrthoDB; 315417at2; -.
DR Proteomes; UP000005766; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd12131; HGbI-like; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR45655; GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2; 1.
DR PANTHER; PTHR45655:SF13; SOLUBLE GUANYLATE CYCLASE GCY-35-RELATED; 1.
DR Pfam; PF00042; Globin; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF46458; Globin-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS01033; GLOBIN; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005766};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 445..497
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 537..664
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT DOMAIN 713..844
FT /note="Globin family profile"
FT /evidence="ECO:0000259|PROSITE:PS01033"
SQ SEQUENCE 876 AA; 97607 MW; BBC97548C1092741 CRC64;
MKVQIPLIHQ LTFKSKLILL TLFASISSVI VIAILSIGLS RRGLRQAAFS QLNVLRSEQA
EQVQNYFQQL QSHTLTLSAN RAIVVAMVEF NKEFRRLDRQ FIPTEWDEPL KRYYEANYFP
RLSDITGSEP RFGSYRPSGQ AARYLQHYYL SQNDYLDAEK NQLITADDDS EYSRYHSEFH
PLLNDIAQQF GYADLYLINQ KTGDIVYSVN KRPDYGTNLE TGAYRDSSLA DLVATVRESS
ARGEVAIADF APYEPASGVP SLFIASPIYN GPYVVGILAI RLETDQISQL MTETLTEDTP
STSLDSYLVG ADGSLRSEPQ FFRDSLSKDD IQSYTRRLRR QGVSDETLAA ITRLESPVLL
QPVKAAAAQS AIGGATDTER LQDYRGVSVL SAYAPLEIEG LDWAVISQID TAEAFATLTH
LELAILVASI LLITAFTFLA MAAATMTIQP VRQLNEWADR VVDGDFEAEI DLDLEDEIGQ
LTDTLQIMVT SLSHQVATLD QKMAQNEVLL TNLVPPAIAK RLKRGETIIA DQIRQITVIY
ANIVGISELS QTLSPEEVTA LLTKLMQAFD DVGEQHGMER QNTPSVDYMA ICGLTTARLD
HTKRTVDFAL EMLKIINLPE FGQSFALGLR LAVHTGPVTA GVVGTKRFGY SVWGESIYLV
TRLYAHAALN SVVLTEAAYQ QIAETYTCVA AGAVAIEKFG RVETWILATR EKLAVRQVEL
VQRSFAKVEP ISEQVGKLFY EHLFETRPDF KPLFSSTDME TQQRKLMMTL ATAVEGLRHP
EEIISKVQAL GRSHQGYGVK AEDYEAIGAT LLWTLKEKLG DDFTPEVKRA WEVAFQFLSK
IMINAAAQIE SDTQAGTELE TEPTTELEIE LKGIEV
//
