ID B5AAU3_HORVV Unreviewed; 442 AA.
AC B5AAU3;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 08-NOV-2023, entry version 86.
DE RecName: Full=Chorismate synthase {ECO:0000256|ARBA:ARBA00013036, ECO:0000256|RuleBase:RU000605};
DE EC=4.2.3.5 {ECO:0000256|ARBA:ARBA00013036, ECO:0000256|RuleBase:RU000605};
OS Hordeum vulgare subsp. vulgare (Domesticated barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=112509 {ECO:0000313|EMBL:ACF36173.1};
RN [1] {ECO:0000313|EMBL:ACF36173.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=19245325; DOI=10.1094/MPMI-22-3-0311;
RA Hu P., Meng Y., Wise R.P.;
RT "Functional contribution of chorismate synthase, anthranilate synthase, and
RT chorismate mutase to penetration resistance in barley-powdery mildew
RT interactions.";
RL Mol. Plant Microbe Interact. 22:311-320(2009).
RN [2] {ECO:0000313|EMBL:BAK02940.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Shoot and root {ECO:0000313|EMBL:BAK02940.1};
RX PubMed=21415278; DOI=10.1104/pp.110.171579;
RA Matsumoto T., Tanaka T., Sakai H., Amano N., Kanamori H., Kurita K.,
RA Kikuta A., Kamiya K., Yamamoto M., Ikawa H., Fujii N., Hori K., Itoh T.,
RA Sato K.;
RT "Comprehensive sequence analysis of 24,783 barley full-length cDNAs derived
RT from 12 clone libraries.";
RL Plant Physiol. 156:20-28(2011).
RN [3] {ECO:0000313|Proteomes:UP000011116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Morex {ECO:0000313|Proteomes:UP000011116};
RX PubMed=23075845; DOI=10.1038/nature11543;
RG The International Barley Genome Sequencing Consortium;
RA Mayer K.F., Waugh R., Brown J.W., Schulman A., Langridge P., Platzer M.,
RA Fincher G.B., Muehlbauer G.J., Sato K., Close T.J., Wise R.P., Stein N.;
RT "A physical, genetic and functional sequence assembly of the barley
RT genome.";
RL Nature 491:711-716(2012).
RN [4] {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.4HG0391140.1}
RP IDENTIFICATION.
RC STRAIN=subsp. vulgare
RC {ECO:0000313|EnsemblPlants:HORVU.MOREX.r3.4HG0391140.1};
RG EnsemblPlants;
RL Submitted (JAN-2022) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate +
CC phosphate; Xref=Rhea:RHEA:21020, ChEBI:CHEBI:29748,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57701; EC=4.2.3.5;
CC Evidence={ECO:0000256|RuleBase:RU000605};
CC -!- COFACTOR:
CC Name=FMNH2; Xref=ChEBI:CHEBI:57618;
CC Evidence={ECO:0000256|RuleBase:RU000605};
CC Note=Reduced FMN (FMNH(2)). {ECO:0000256|RuleBase:RU000605};
CC -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC 7/7. {ECO:0000256|ARBA:ARBA00005044, ECO:0000256|RuleBase:RU000605}.
CC -!- SIMILARITY: Belongs to the chorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00008014, ECO:0000256|RuleBase:RU000605}.
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DR EMBL; EU828767; ACF36173.1; -; mRNA.
DR EMBL; AK371742; BAK02940.1; -; mRNA.
DR AlphaFoldDB; B5AAU3; -.
DR SMR; B5AAU3; -.
DR STRING; 112509.B5AAU3; -.
DR PaxDb; 4513-MLOC_66898-1; -.
DR EnsemblPlants; HORVU.MOREX.r3.4HG0391140.1; HORVU.MOREX.r3.4HG0391140.1; HORVU.MOREX.r3.4HG0391140.
DR Gramene; HORVU.MOREX.r2.4HG0325400.1; HORVU.MOREX.r2.4HG0325400.1; HORVU.MOREX.r2.4HG0325400.
DR Gramene; HORVU.MOREX.r2.4HG0325400.1.mrna1; HORVU.MOREX.r2.4HG0325400.1.mrna1; HORVU.MOREX.r2.4HG0325400.1.
DR Gramene; HORVU.MOREX.r3.4HG0391140.1; HORVU.MOREX.r3.4HG0391140.1; HORVU.MOREX.r3.4HG0391140.
DR eggNOG; KOG4492; Eukaryota.
DR OrthoDB; 275401at2759; -.
DR BRENDA; 4.2.3.5; 2687.
DR UniPathway; UPA00053; UER00090.
DR Proteomes; UP000011116; Chromosome 4H.
DR ExpressionAtlas; B5AAU3; baseline and differential.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0004107; F:chorismate synthase activity; IBA:GO_Central.
DR GO; GO:0010181; F:FMN binding; IBA:GO_Central.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IBA:GO_Central.
DR GO; GO:0009423; P:chorismate biosynthetic process; IBA:GO_Central.
DR CDD; cd07304; Chorismate_synthase; 1.
DR Gene3D; 3.60.150.10; Chorismate synthase AroC; 1.
DR HAMAP; MF_00300; Chorismate_synth; 1.
DR InterPro; IPR000453; Chorismate_synth.
DR InterPro; IPR035904; Chorismate_synth_AroC_sf.
DR InterPro; IPR020541; Chorismate_synthase_CS.
DR NCBIfam; TIGR00033; aroC; 1.
DR PANTHER; PTHR21085; CHORISMATE SYNTHASE; 1.
DR PANTHER; PTHR21085:SF0; CHORISMATE SYNTHASE; 1.
DR Pfam; PF01264; Chorismate_synt; 1.
DR SUPFAM; SSF103263; Chorismate synthase, AroC; 1.
DR PROSITE; PS00787; CHORISMATE_SYNTHASE_1; 1.
DR PROSITE; PS00788; CHORISMATE_SYNTHASE_2; 1.
DR PROSITE; PS00789; CHORISMATE_SYNTHASE_3; 1.
PE 2: Evidence at transcript level;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605,
KW ECO:0000256|RuleBase:RU000605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141,
KW ECO:0000256|RuleBase:RU000605};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000605};
KW Reference proteome {ECO:0000313|Proteomes:UP000011116}.
FT REGION 90..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 442 AA; 47223 MW; 24FF1FEAF9D697D4 CRC64;
MAAAPTSHQL AAGAGAPWSS LPRGGFRALT DSAPASVRFS VARRRAARLE VKAAGNIFGD
YFQVATYGES HGGGVGCVIS GCPPRIPLTE EDMQGDLDRR RPGQSRITTP RKETDTCKIL
SGTYEGMTTG TPIHVFVPNT DQRGGDYTEM AKAYRPSHAD LTYDLKYGVR SVQGGGRSSA
RETIGRVAAG AVAKKILKLK CGVEILAFVS KVHQVVLPED AVDYETLTLD QIESNICRCP
DPEYAQKMID AIDKVRINGN SIGGVVTCIA RNVPRGLGSP VFDKLEALLA KAMLSLPASK
GFEIGSGFAG TDLTGSEHND EFYMDEGGNV RTRTNRSGGV QGGISNGETI YFKVAFKPTA
TIGKKQNTVT RDHEDIELLT RGRHDPCVVP RAVPMVETMA ALVLMDQLMA HVAQCEMFPL
NLALQEPIGS ANSTPALAPD LA
//
