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Database: UniProt
Entry: B5DZ45_DROPS
LinkDB: B5DZ45_DROPS
Original site: B5DZ45_DROPS 
ID   B5DZ45_DROPS            Unreviewed;      1465 AA.
AC   B5DZ45;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 2.
DT   12-SEP-2018, entry version 50.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDY69144.2};
GN   Name=Dpse\GA24859 {ECO:0000313|EMBL:EDY69144.2};
GN   ORFNames=Dpse_GA24859 {ECO:0000313|EMBL:EDY69144.2}, GA24859
GN   {ECO:0000313|FlyBase:FBgn0246244};
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245 {ECO:0000313|EMBL:EDY69144.2, ECO:0000313|Proteomes:UP000001819};
RN   [1] {ECO:0000313|EMBL:EDY69144.2, ECO:0000313|Proteomes:UP000001819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94
RC   {ECO:0000313|Proteomes:UP000001819};
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P.,
RA   Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J.,
RA   van Batenburg M.F., Howells S.L., Scherer S.E., Sodergren E.,
RA   Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D.,
RA   Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D.,
RA   Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R.,
RA   Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L.,
RA   Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura:
RT   chromosomal, gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
RN   [2] {ECO:0000313|EMBL:EDY69144.2, ECO:0000313|Proteomes:UP000001819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94
RC   {ECO:0000313|Proteomes:UP000001819};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CM000071; EDY69144.2; -; Genomic_DNA.
DR   RefSeq; XP_002138586.2; XM_002138550.3.
DR   STRING; 7237.FBpp0308023; -.
DR   EnsemblMetazoa; FBtr0377222; FBpp0338292; FBgn0246244.
DR   GeneID; 6898566; -.
DR   KEGG; dpo:Dpse_GA24859; -.
DR   FlyBase; FBgn0246244; Dpse\GA24859.
DR   InParanoid; B5DZ45; -.
DR   KO; K10895; -.
DR   Proteomes; UP000001819; Chromosome 3.
DR   Bgee; FBgn0246244; Expressed in 5 organ(s), highest expression level in female reproductive system.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd11720; FANCI; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR026171; FANCI.
DR   InterPro; IPR029312; FANCI_HD2.
DR   InterPro; IPR029308; FANCI_S1.
DR   InterPro; IPR029315; FANCI_S2.
DR   InterPro; IPR029313; FANCI_S3.
DR   InterPro; IPR029314; FANCI_S4.
DR   PANTHER; PTHR21818; PTHR21818; 1.
DR   Pfam; PF14680; FANCI_HD2; 1.
DR   Pfam; PF14675; FANCI_S1; 1.
DR   Pfam; PF14676; FANCI_S2; 1.
DR   Pfam; PF14677; FANCI_S3; 1.
DR   Pfam; PF14678; FANCI_S4; 1.
DR   SUPFAM; SSF48371; SSF48371; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001819};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001819}.
FT   DOMAIN       67    286       FANCI_S1. {ECO:0000259|Pfam:PF14675}.
FT   DOMAIN      391    531       FANCI_S2. {ECO:0000259|Pfam:PF14676}.
FT   DOMAIN      556    776       FANCI_HD2. {ECO:0000259|Pfam:PF14680}.
FT   DOMAIN      821   1038       FANCI_S3. {ECO:0000259|Pfam:PF14677}.
FT   DOMAIN     1049   1303       FANCI_S4. {ECO:0000259|Pfam:PF14678}.
FT   COILED     1412   1432       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1465 AA;  168060 MW;  13766AEFC74961D4 CRC64;
     MSRDSLELQV RKYGERGQRD ELELLIKNTS VKQLTDTLNA TISRSEGINF WNYFLLACDT
     ESEESKKKRF ALVQCFMDGL RSIELNYKQS FDLITRLAQD LPTFSADELA WIIEHCVDGM
     RQGDAKCVGW KDLLPDSLAL LSATPRFILN GVGTDGTEYR NNTVKSICTM RWPSSILTPI
     ADMFKAINLS NGEILTVLNK FSGALQELSP MELPALCFQL FSMCQNASQL IVPLLALEKY
     FQRNYYKRLF SDMSSNSTDF DSIDPFSDKE LREAEETILH HLNYCTMYKL TEKHLAIMLR
     NFSHLPDVIL TPFMLSAIIS MTSVNRDPET ARISRSILLP FLRNVIKNNE EEITLADYSV
     WYRDSLQRKQ VDLQQVLTVL IDQNKDGKDV ITPGLVHLVF FLLKSHSPKM HTLAITFLTK
     FIRKRFIFGQ GIIRLLSEWM IVHQDQNQFS ECLTLLSVAD TYTVSECTKT IQTVMEHMLW
     LPGEQAMRMM NFLLPLLKIS NRVRDALIDV LCKAMGSSGM QKRRMAIYGF CMILKQLNNS
     NALRQTSSAT SFCTQQSISG YSMMTQNSLG SRSNPQRNFD MLTLEIIGML RNCLQQQFDI
     RCTLYENLQR AVELNAKLVP HVLQVIDWHF RSFFDTPSAE EAGDDLDTVF RIRYDQLVTA
     SDQQHMEIQL KDNLGKLVQF VANCLVTFER APSGYDTREI SRLLALCVQR MVANRLPIDD
     VSPPATHLKC ALVLQQLNLI EGIVSHLLLS SKPSNDAICQ VLPLFKQHCK LLDDLKTLAG
     SSKKLQKQSK KTVSNDTTTS IFNLTVNGIP MKSMCTQTEN IWDLSILDKL LHLLLDDVVP
     FAASEKTIQL RSNESLVRYV VQITAEKVKN IRLEPDYKQL AYSKRTFKQL TDITKIIYER
     CIRRLPELWR DFDMQTSSLA AQCFVECLRT AHETYSKKFN EYVKGFDMAS LNRSKAVTYV
     VQDVLDEFMK EFASDDSLNK DTFIAKLPVY LLESLEILFD HIDYGERAAT ESYTWLLNFC
     RTHELLNPEL GLVHNLLFIQ RQKTHSGPFF ESIARQLGHV LGALNDDISI DLPDPGLKSI
     STITAESCLQ HLYVAVQKQL LNVEYFVVKA NNLSYKCQLV PESDQSYWRG NLDVMERSIC
     TQIIHITRTL LALTNVCIPL GSSMDGLMKL LIQHYICLKN LTRHYLSCCT SDASNANMRS
     TKFELLLREV GKQLPANVYE LITYIEANTL DEDNQHIKTR NVQAQRAKVL RETRLIPKVI
     MVIEDFNKHI ILLSKKTKTF NRLTDYLHLG TMRDFDIKST DLKAAIERSL TDTHEVAEDD
     CTTEDMEDID HSNDPSNDEE DEAETEIIQA PNKRQRQRRA PISDTEESQP KRTRGQKTKV
     VQSAKPQSND EQESNEEQLE TIQTTKLRNR TKKRQTKKST RLSNEEESAE ERGLTEQRTK
     DMRKSQERDT GVKPRRLGLL RSGKK
//
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