GenomeNet

Database: UniProt
Entry: B5FF87
LinkDB: B5FF87
Original site: B5FF87 
ID   RHLB_ALIFM              Reviewed;         432 AA.
AC   B5FF87;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   16-OCT-2019, entry version 69.
DE   RecName: Full=ATP-dependent RNA helicase RhlB {ECO:0000255|HAMAP-Rule:MF_00661};
DE            EC=3.6.4.13 {ECO:0000255|HAMAP-Rule:MF_00661};
GN   Name=rhlB {ECO:0000255|HAMAP-Rule:MF_00661};
GN   OrderedLocusNames=VFMJ11_0054;
OS   Aliivibrio fischeri (strain MJ11) (Vibrio fischeri).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Aliivibrio.
OX   NCBI_TaxID=388396;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MJ11;
RA   Mandel M.J., Stabb E.V., Ruby E.G., Ferriera S., Johnson J.,
RA   Kravitz S., Beeson K., Sutton G., Rogers Y.-H., Friedman R.,
RA   Frazier M., Venter J.C.;
RT   "Complete sequence of Vibrio fischeri strain MJ11.";
RL   Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DEAD-box RNA helicase involved in RNA degradation. Has
CC       RNA-dependent ATPase activity and unwinds double-stranded RNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00661};
CC   -!- SUBUNIT: Component of the RNA degradosome, which is a multiprotein
CC       complex involved in RNA processing and mRNA degradation.
CC       {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. RhlB
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00661}.
DR   EMBL; CP001139; ACH65016.1; -; Genomic_DNA.
DR   RefSeq; WP_012532773.1; NC_011184.1.
DR   SMR; B5FF87; -.
DR   EnsemblBacteria; ACH65016; ACH65016; VFMJ11_0054.
DR   KEGG; vfm:VFMJ11_0054; -.
DR   HOGENOM; HOG000268807; -.
DR   KO; K03732; -.
DR   OMA; TRFHDFK; -.
DR   Proteomes; UP000001857; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00661; DEAD_helicase_RhlB; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR023554; RNA_helicase_ATP-dep_RhlB.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase;
KW   Nucleotide-binding; RNA-binding.
FT   CHAIN         1    432       ATP-dependent RNA helicase RhlB.
FT                                /FTId=PRO_1000131312.
FT   DOMAIN       40    219       Helicase ATP-binding. {ECO:0000255|HAMAP-
FT                                Rule:MF_00661}.
FT   DOMAIN      245    390       Helicase C-terminal. {ECO:0000255|HAMAP-
FT                                Rule:MF_00661}.
FT   NP_BIND      53     60       ATP. {ECO:0000255|HAMAP-Rule:MF_00661}.
FT   MOTIF         9     37       Q motif.
FT   MOTIF       165    168       DEAD box.
SQ   SEQUENCE   432 AA;  48620 MW;  A75FB6CC8D8FD752 CRC64;
     MKKTHITEQN FADLGLQPQV IDGLNAKGFI KCTPIQAKAL PVLLAGQDIA GQAQTGTGKT
     LAFLTATFNH LLTTPAPEGR KITQPRAIIM APTRELAIQI FNDAESLIAS TGLKAALAYG
     GERYEKQQQV IEQGVDILIG TTGRIIDFYK QGHIDFKMIQ AVVLDEADRM FDLGFIKDIR
     FIFRRMPAPT ERLNMLFSAT LSYRVQELAF EHMQEPEHVV VEPEQKTGHR IKEELFYPSN
     DHKMALLQTL IEEEWPDRAI IFANTKHKCE SVWGHLAADK HRVGLLTGDV PQKKRERILE
     EFTQGNVDIL VATDVAARGL HIPQVTHVFN FDLPNEAEDY VHRIGRTGRA GASGNSISFA
     CEEYAINLPA IEEYIEHSIP QSDYDASALL EDLPAPLRLQ RRPQQNRRNN NGQRQGGNRK
     HSRPRQPRNT QS
//
DBGET integrated database retrieval system