ID B5G8B8_STRSH Unreviewed; 881 AA.
AC B5G8B8;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Beta-glucosidase {ECO:0000313|EMBL:EDY42564.3};
DE Flags: Fragment;
GN ORFNames=SSBG_00526 {ECO:0000313|EMBL:EDY42564.3};
OS Streptomyces sp. (strain SPB074).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=465543 {ECO:0000313|EMBL:EDY42564.3, ECO:0000313|Proteomes:UP000002779};
RN [1] {ECO:0000313|Proteomes:UP000002779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG The Broad Institute Genome Sequencing Platform;
RA Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Straight P., Clardy J.,
RA Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T., Lander E.,
RA Galagan J., Nusbaum C., Birren B.;
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDY42564.3, ECO:0000313|Proteomes:UP000002779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain SPB74.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG770539; EDY42564.3; -; Genomic_DNA.
DR AlphaFoldDB; B5G8B8; -.
DR Proteomes; UP000002779; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008422; F:beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102483; F:scopolin beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR037524; PA14/GLEYA.
DR InterPro; IPR011658; PA14_dom.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF10; BETA-GLUCOSIDASE F-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR Pfam; PF07691; PA14; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS51820; PA14; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 847..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 449..605
FT /note="PA14"
FT /evidence="ECO:0000259|PROSITE:PS51820"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 881
FT /evidence="ECO:0000313|EMBL:EDY42564.3"
SQ SEQUENCE 881 AA; 94366 MW; 3C9EA21221A76EAA CRC64;
MSRKNNVPYR TTGRRVQDEC ALPPDRGRGP RSPRTATTRS TAVTGASTPP EPQVTPERQA
AHEAAVETAL ARLDLDTKTR LLAGQDFWSL PAIPEIGLDS LVVSDGPIGV RGVRSTSEDP
SLALPSPTAL SATWSPETAV RAGQVLAQEA RRKGVHVLLA PTVNLHRSPL GGRHFEAYSE
DPYLTGAIGT GYVRGVQSGG VGTTVKHFVG NDAETDRFTV DNRIAPRPLR ELYLAPFEAI
VANARPWGIM TAYNTVNGTT MTEHRYLVNE VLRGEWKFDG VNVSDWTAAR DTVADANGGL
DLAMPGPKTV YGENLAAAVR AGEVEESVVD EAVRRVLLLA ARTGALKTTE PVVPTEALPA
EIDGEAFARE LATRSFVLVR NEDSALPLAP GTRVALSGAA AREARVLGGG SATVFPAHVV
APLDGLRAAL PEGALSYEVG ADPNNELDVA GQGFALRAVC RDASGEILAT VPLAGGHIQW
MGSDLPDGVT YDALHSIEVT GTFTPRESGE HVFGTRGIGG FKVVIAGREL FEGSVEMGAA
TDPFEAFFGQ PTERGRLELA AGEPVELSVF HTVAKPEGLP IQAVGFTVLH QNPVHDPDEL
IARAAEAARA ADTAVVVVAT TERVESEGFD RADLGLPGRQ DDLVRAVAAA NPRTVVVVNA
GSPVEMPWRE DVAAVLLSWF PGQEGGAALA DVLTGAAEPG GRLPTTWPAV LADAPVVNTT
PTGGKLEYTE GVLIGYRAWE QAGRTPAYPF GHGFGYTDWT YESVTVEPAA ENGLTVTVRV
RNSGGRAGRE TVQVYLAPAE PGTGPATERP ARWLAGFAQV EAAPGESAEA VVRVARRAFE
IWDEEKGAWH LFFFFFFFFF FFFFFFFFFF FFFFFFFFFF F
//
