ID B5GI66_STRSH Unreviewed; 487 AA.
AC B5GI66;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Integral membrane protein {ECO:0000313|EMBL:EDY46012.3};
DE Flags: Fragment;
GN ORFNames=SSBG_04039 {ECO:0000313|EMBL:EDY46012.3};
OS Streptomyces sp. (strain SPB074).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=465543 {ECO:0000313|EMBL:EDY46012.3, ECO:0000313|Proteomes:UP000002779};
RN [1] {ECO:0000313|Proteomes:UP000002779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG The Broad Institute Genome Sequencing Platform;
RA Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Straight P., Clardy J.,
RA Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T., Lander E.,
RA Galagan J., Nusbaum C., Birren B.;
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDY46012.3, ECO:0000313|Proteomes:UP000002779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces sp. strain SPB74.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC {ECO:0000256|ARBA:ARBA00038076}.
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DR EMBL; GG770539; EDY46012.3; -; Genomic_DNA.
DR RefSeq; WP_008747702.1; NZ_GG770539.1.
DR AlphaFoldDB; B5GI66; -.
DR OrthoDB; 4832961at2; -.
DR Proteomes; UP000002779; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR025857; MacB_PCD.
DR PANTHER; PTHR30572:SF4; MACROLIDE EXPORT ATP-BINDING_PERMEASE PROTEIN MACB; 1.
DR PANTHER; PTHR30572; MEMBRANE COMPONENT OF TRANSPORTER-RELATED; 1.
DR Pfam; PF02687; FtsX; 1.
DR Pfam; PF12704; MacB_PCD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 334..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 182..298
FT /note="MacB-like periplasmic core"
FT /evidence="ECO:0000259|Pfam:PF12704"
FT DOMAIN 335..483
FT /note="ABC3 transporter permease protein"
FT /evidence="ECO:0000259|Pfam:PF02687"
FT REGION 65..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 487
FT /evidence="ECO:0000313|EMBL:EDY46012.3"
SQ SEQUENCE 487 AA; 48874 MW; E0C7FD15694776A6 CRC64;
MFFTCLRREL RRRRKAALVV ASGLALGIAL VIVVNSVAAG MNKAQDKVLQ SLYGLGTDLT
VTKAAAAPQE GGTGSRPRFD FDAKDSDDDS EQSSDRVLVQ GFQTLASSTV TKVSAQDGVA
QAVGGLSLQV MKVNGQFTRG EFKQDGSAGS GGRGGPGGGS GGGTQPPGGE VRGGGAQFDV
DSYSVYGTDV AHPALGPLTS SRITKGRTFT TSETNARLAV VDSAYAKEKK LSTGDELTVH
GTKFEIIGIA TADSGDAAAN VYVPLRQAQT LADSKNKVTT VYVKAADSKK IDSVKSAVLK
QVPGTTVTTS ADLADTVSGS LSTASSLATG VGRWLSAVVL AAAFLVAGLL TVSAVGRRVR
EFGTLKALGW SSARVNRQVV GEAVVNGLIG GALGIAVGLL GAWIVSLAGP TLTAELGSSA
ARGAGGAGGG PGGFGGPARQ AAQKALTVSL EAPVSATTVV LAVVLALGGG LVAGAFGGWR
ATRLRPG
//
