ID B5HAA5_STRE2 Unreviewed; 462 AA.
AC B5HAA5;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal domain-containing protein {ECO:0000259|SMART:SM01003};
GN ORFNames=SSDG_02185 {ECO:0000313|EMBL:EDY63766.1};
OS Streptomyces pristinaespiralis (strain ATCC 25486 / DSM 40338 / CBS 914.69
OS / JCM 4507 / NBRC 13074 / NRRL 2958 / 5647).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=457429 {ECO:0000313|EMBL:EDY63766.1, ECO:0000313|Proteomes:UP000002805};
RN [1] {ECO:0000313|Proteomes:UP000002805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25486 / DSM 40338 / CBS 914.69 / JCM 4507 / NBRC 13074 /
RC NRRL 2958 / 5647 {ECO:0000313|Proteomes:UP000002805};
RG The Broad Institute Genome Sequencing Platform;
RA Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Straight P., Clardy J.,
RA Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T., Lander E.,
RA Galagan J., Nusbaum C., Birren B.;
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25486 / DSM 40338 / CBS 914.69 / JCM 4507 / NBRC 13074 /
RC NRRL 2958 / 5647 {ECO:0000313|Proteomes:UP000002805};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Streptomyces pristinaespiralis strain ATCC 25486.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM000950; EDY63766.1; -; Genomic_DNA.
DR AlphaFoldDB; B5HAA5; -.
DR eggNOG; COG0169; Bacteria.
DR eggNOG; COG0686; Bacteria.
DR HOGENOM; CLU_582429_0_0_11; -.
DR Proteomes; UP000002805; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR007886; AlaDH/PNT_N.
DR PANTHER; PTHR42795; ALANINE DEHYDROGENASE; 1.
DR PANTHER; PTHR42795:SF1; ALANINE DEHYDROGENASE 1; 1.
DR Pfam; PF05222; AlaDh_PNT_N; 1.
DR SMART; SM01003; AlaDh_PNT_N; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002805}.
FT DOMAIN 27..163
FT /note="Alanine dehydrogenase/pyridine nucleotide
FT transhydrogenase N-terminal"
FT /evidence="ECO:0000259|SMART:SM01003"
SQ SEQUENCE 462 AA; 50468 MW; 3CA01E3D28BBD70C CRC64;
MAGGEVLRDD QRRLHGLRRG SGMTTILFAK ESDCEENPGG HDLRATLVPQ DVRRYVDRGF
DVVIQQGLGE GIGYLDRQYE LEGARVEPYP SCYGGKDLVV KLKGPSAAEV AQLSYGTTLF
SMGHLYCFPE RERLLRDKGV RLVGMETVTD PQEPSDGYLA GIAAGSGVDV DALGPEPEVL
IDSSAPQEYV NGLLRSLMRY GRKPLRVRYT DTDGPEQSRA AVSGSAVLTA GDGVTDLAPA
VGAPYRLGEE DLPAGRDGLL AEERGKPVRA IGQIREVGIG GTKYGLDLFR SRNAGRTPEV
LVLGYGNCSM GAFEHLRDRR VEFTVLGRPQ TSPEELPGRL ASAQLIVNGA ETPGQSEYII
TRRNAERDVP VGAVVIDLIG GSPALRSPVE SFVWTTFLPD IHFEEHGRFF AGLWGWDMYY
SMHDTALEYS RRIAKVLTSG DRYAKSLDDF VSDYAYALQL EG
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