ID   B5JCT4_9BACT            Unreviewed;       455 AA.
AC   B5JCT4;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   SubName: Full=Uroporphyrinogen decarboxylase superfamily {ECO:0000313|EMBL:EDY83965.1};
GN   ORFNames=VDG1235_3592 {ECO:0000313|EMBL:EDY83965.1};
OS   Verrucomicrobiae bacterium DG1235.
OC   Bacteria; Verrucomicrobiota; Verrucomicrobiae.
OX   NCBI_TaxID=382464 {ECO:0000313|EMBL:EDY83965.1, ECO:0000313|Proteomes:UP000003839};
RN   [1] {ECO:0000313|EMBL:EDY83965.1, ECO:0000313|Proteomes:UP000003839}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG1235 {ECO:0000313|EMBL:EDY83965.1,
RC   ECO:0000313|Proteomes:UP000003839};
RA   Hart M., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS990592; EDY83965.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5JCT4; -.
DR   STRING; 382464.VDG1235_3592; -.
DR   eggNOG; COG0407; Bacteria.
DR   HOGENOM; CLU_040933_2_2_0; -.
DR   OrthoDB; 9780425at2; -.
DR   Proteomes; UP000003839; Unassembled WGS sequence.
DR   GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR   CDD; cd03465; URO-D_like; 1.
DR   Gene3D; 3.20.20.210; -; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR   PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   Pfam; PF13192; Thioredoxin_3; 1.
DR   Pfam; PF01208; URO-D; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000003839}.
FT   DOMAIN          3..333
FT                   /note="Uroporphyrinogen decarboxylase (URO-D)"
FT                   /evidence="ECO:0000259|Pfam:PF01208"
FT   DOMAIN          375..445
FT                   /note="Thioredoxin-like fold"
FT                   /evidence="ECO:0000259|Pfam:PF13192"
SQ   SEQUENCE   455 AA;  48770 MW;  48A0B239C9BD5B01 CRC64;
     MTGKEILLRA LKCEATPRVP WVPFVGVHGG ALIGVDAKDY LESTEHIVSG LKASAKRYRP
     DGLPVVFDLQ LEAEVLGCQL AWAQETPPAV ISHPLDAGYA IKALPTLSVE KGRLPLALQA
     IRETKKELGE EIALYGLLTG PLTLALHLRG DDVLLDMFDE EEGVVALLDY CAEIANQMVD
     AYLDAGIDVI AVVDPMISQI GPSHFTDWVA PRLDEVFSYV RKKGALSSLF VCGNATRNLA
     AMCATQCDNI SVDENVDLAE LAKVARAAGK SFGGNLQLTK ILLLGDEADA KREVVRCLDQ
     AGDGGGFILA PGCDLPYAVK PENLEAVAAL VHDPYLIEVA RNLPPKDSTD TFDDIPIPDY
     AAENQVLVDI VTLDSAGCAP CAYMLKAAQK AADEYGGTID VREHKITTRD GLAYMAKLGV
     TAIPSICVDG RERFASIIPQ RKELVACYQT AAAAK
//