ID B5JJ49_9BACT Unreviewed; 717 AA.
AC B5JJ49;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Transporter, CPA2 family {ECO:0000313|EMBL:EDY82229.1};
GN ORFNames=VDG1235_1849 {ECO:0000313|EMBL:EDY82229.1};
OS Verrucomicrobiae bacterium DG1235.
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae.
OX NCBI_TaxID=382464 {ECO:0000313|EMBL:EDY82229.1, ECO:0000313|Proteomes:UP000003839};
RN [1] {ECO:0000313|EMBL:EDY82229.1, ECO:0000313|Proteomes:UP000003839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG1235 {ECO:0000313|EMBL:EDY82229.1,
RC ECO:0000313|Proteomes:UP000003839};
RA Hart M., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS990592; EDY82229.1; -; Genomic_DNA.
DR AlphaFoldDB; B5JJ49; -.
DR STRING; 382464.VDG1235_1849; -.
DR eggNOG; COG0025; Bacteria.
DR eggNOG; COG0569; Bacteria.
DR HOGENOM; CLU_005912_10_1_0; -.
DR OrthoDB; 570124at2; -.
DR Proteomes; UP000003839; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003839};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..389
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT DOMAIN 402..480
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02254"
FT DOMAIN 592..711
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|Pfam:PF00359"
SQ SEQUENCE 717 AA; 77854 MW; 48F7156272537A83 CRC64;
MDSDIAFRTI ALALGVGLLL TVIAHKFDFP TIVLLFAGGL ALGPAGLGWI DPQSLGHVMP
VIVSLSIGII LFEGGLTLKP ADYTASPTII KLLLTVGVLV TWLCAAAAIY FIFQASWQIS
LLSGSLVVVT GPTVIVPMLH RLRLKDKLGS ILHWEGVLID PIGVFVAVFC YELVVVEDGS
SAIAGLALRL LVGLILGAIG GVAIQQCLER KWIPDSLTNP FALAAAVLVF TCAELISHES
GLLAVTVAGV VVARRRSSEV RQIKAFKAEL TDILIATLFL LLVSRLDPAV FLQDLWKLVA
AAAVVMLIGR PLNILLCSIG SGLTGREKLF LAWVAPRGIV AASMASLFAL QLSESPEHAA
ESGIVETFVY TIICGTVIIQ GLSAGWWARK LRVSRGKADG WLIVGAHALG RGIARIMVEN
GRNVLLVDSN QRNIDAAKRD GLQAALEDAR EAEDLRDDER FQNVGQLIAL TDNVDLNELV
ANRWLPFLGR SKLHAWSPRS GADNSEALDT VFNDLPEPSI ASEELTHGTA QLELSQDPIA
DGEIPLMCLG DSGFTLLSRN EKPATNNILR LVRQRSHLGR AIERGGIYRL AKLKDLDTIY
HKLCDQAVLK DPRLDRPTLI EDLEEMARRR SPIFGDDVSA LHLYSPVLER TLCFLAWLET
PVTSRSGRTQ VEFVFLLISP TNDSEEPLPL LAQFVHLCHD HDALEAWAAK QETTDPI
//
