ID   B5JMM5_9BACT            Unreviewed;       543 AA.
AC   B5JMM5;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   24-JAN-2024, entry version 53.
DE   SubName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase, putative {ECO:0000313|EMBL:EDY85014.1};
DE            EC=1.17.1.2 {ECO:0000313|EMBL:EDY85014.1};
GN   ORFNames=VDG1235_4648 {ECO:0000313|EMBL:EDY85014.1};
OS   Verrucomicrobiae bacterium DG1235.
OC   Bacteria; Verrucomicrobiota; Verrucomicrobiae.
OX   NCBI_TaxID=382464 {ECO:0000313|EMBL:EDY85014.1, ECO:0000313|Proteomes:UP000003839};
RN   [1] {ECO:0000313|EMBL:EDY85014.1, ECO:0000313|Proteomes:UP000003839}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG1235 {ECO:0000313|EMBL:EDY85014.1,
RC   ECO:0000313|Proteomes:UP000003839};
RA   Hart M., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; DS990592; EDY85014.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5JMM5; -.
DR   STRING; 382464.VDG1235_4648; -.
DR   eggNOG; COG0761; Bacteria.
DR   HOGENOM; CLU_027486_4_0_0; -.
DR   Proteomes; UP000003839; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051745; F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:InterPro.
DR   GO; GO:0019288; P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; IEA:InterPro.
DR   CDD; cd13944; lytB_ispH; 1.
DR   Gene3D; 3.40.50.11270; -; 1.
DR   Gene3D; 3.40.1010.20; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain; 2.
DR   InterPro; IPR003451; LytB/IspH.
DR   NCBIfam; TIGR00216; ispH_lytB; 1.
DR   PANTHER; PTHR31619; 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR31619:SF5; 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC; 1.
DR   Pfam; PF02401; LYTB; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000313|EMBL:EDY85014.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003839}.
SQ   SEQUENCE   543 AA;  61278 MW;  5D2DC3869FC0FD0B CRC64;
     MVVRRGKNCG KLKPFAFGPA AIAEARAMLD KLGRSEKAVE VEEGLYFVAL DEMELPEAWA
     AGGWMAEPLR VFYEEAKLPA EWMDRIRRNA IRVPYLYLNS NDFIYRFRAE RERNRKIYQV
     DDRSVALYQS ALCDAIKAVK RGKERSATSP ARLDFGATEY LLPSHFGFCL GVQNAIERAY
     ETLAANPGKR VFMLSELIHN PFVNEDLQAR GLKYLQSDKG VPLIEEATGR PYWDGLSDAD
     IVIIPAFGAR DEDKLRLIER GLPIRQYDAT CMLVEKVWKA ARRYGEQGYT IVIHGKAEHE
     ETKATFSNSA KYAPSVVIRD IKEASILGEV IRAKSKEEKQ RLFEPFVSRA SVGFDPSKDL
     DRLALVNQTT LLRNETLKII AYLEETLAET YGEAHVKEHL AMSSKGDTLC YATQVNQDAL
     AKALDEDIDA AIVVGGKNSS NTFQLFRLCQ ERFGERAFYI QSEANILSRD EIEHFIFPYN
     PGDPKQGVME TRAFLPEKER VKVLVTGGAS CPDGILQQII CRINGFHAPE RIRSIESVLA
     EIE
//