ID B5LJG4_9CAUD Unreviewed; 1138 AA.
AC B5LJG4;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 1.
DT 13-SEP-2023, entry version 51.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN Name=192 {ECO:0000313|EMBL:ACH62161.1};
GN ORFNames=MYRNA_192 {ECO:0000313|EMBL:ACH62161.1};
OS Mycobacterium phage Myrna.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Ceeclamvirinae; Myrnavirus; Myrnavirus myrna.
OX NCBI_TaxID=546805 {ECO:0000313|EMBL:ACH62161.1, ECO:0000313|Proteomes:UP000001849};
RN [1] {ECO:0000313|EMBL:ACH62161.1, ECO:0000313|Proteomes:UP000001849}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Smith A.L., Paladin E.C., Jacobs-Sera D., Hendirx R.W., Hatfull G.F.;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; EU826466; ACH62161.1; -; Genomic_DNA.
DR RefSeq; YP_002225071.1; NC_011273.1.
DR GeneID; 6920896; -.
DR KEGG; vg:6920896; -.
DR Proteomes; UP000001849; Genome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.870; -; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR011708; DNA_pol3_alpha_NTPase_dom.
DR InterPro; IPR040982; DNA_pol3_finger.
DR InterPro; IPR004805; DnaE2/DnaE/PolC.
DR InterPro; IPR029460; DNAPol_HHH.
DR InterPro; IPR004013; PHP_dom.
DR InterPro; IPR003141; Pol/His_phosphatase_N.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR NCBIfam; TIGR00594; polc; 1.
DR PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR PANTHER; PTHR32294:SF0; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR Pfam; PF07733; DNA_pol3_alpha; 1.
DR Pfam; PF17657; DNA_pol3_finger; 1.
DR Pfam; PF14579; HHH_6; 1.
DR Pfam; PF02811; PHP; 1.
DR SMART; SM00481; POLIIIAc; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000001849};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 9..76
FT /note="Polymerase/histidinol phosphatase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00481"
SQ SEQUENCE 1138 AA; 129636 MW; E45845431B85D9F9 CRC64;
MSISNADYVA LHNHGDTSFL DGRARHEEIV ERAVELGNEA VSLTDHDEVN GHINMWNLCQ
KAGIKFVPGA EQRWLMDPEE SRRLSTSGYD YSHICLLAEN NEGLKNLWTL SSLAYEPGNF
YRYPQLNPPL MKQYASGLWA SDGCGLTRFA GYIEEDDEES ARQEWAVLLD IFGDRFYSEL
HTFKFLESED RPLDAKEREI NAKITKMNHA KVRFAQEMGV PLVVVNDAHY AWERDWKQHR
LVWKMNTKNK KDQSEGNAHA ADWMMSADEL VHYMGLHGIS RSIVEEAVKN TRMIADSCTV
EIKPTINMPR LHDTDEEDRA AFLRSCEEGF KRFVTDKGLD EETYRARLER EQKLIIDKDF
YGYFNVVSDY MLAARSGEYI KWVKPGAKPK PCICGPGRGS GGGSLVNYLL GITSLDPIKY
DLSFERFINP DRPDFPDIDV DFQKSHRKDL LGYMAARYGG DKVVAIGTKA KSGPARAIQD
LCKALGIDFK DSLAMSKLIK KVDFSDTNDY EVNPDYVPPT WEETLELIGG ELQPYMEKYA
DTGLFRYAQD MVGLSRQAGV HAAGIFMDTD PILGKAPTRR KGGSPDAPVA TQFDMEEMAW
LGAVKMDFLS NKGLDVLSIA RDLIWERHGK WIDYDGFLYG APPEGAEIIH MDDDKYADPT
IWEQIDLGHT AGIFQINTPS GTKQAKRFKP RNLKDLADLV SVNRPGVLRV PGLLDRYMRR
RHGEEEITYD HPLLEQVTGH TMGILVYQED LVAACRLLAN FTPGEGETLR KAIGKKKLDL
MQSFKGQFLE GCMANREFTR QGGNRALAER IWQQMIASAS YAFNKAHAMG YAMQAVQEIW
VKAHYFQEFE TGCLAVYGED VKDGEKKSLV FLRECRRRKQ PVLPPDVNQS QERFSLTDDG
IRYGLIDING IGPSVIPDII KNRPYVDLQD YLDRTKKGLG GKRGVVDNLV KIGAFDWTGQ
SRSDMLDQVY YHWCRMEIAE KKRNSISVEE TDKIVWDKWR KNPDKFPRFK FDKPEVVQKI
EEDLVGTFIT RDPMGPYVSM IEGECIQHPT DMEDFRTGQR FVIGGELMRI HKHQARNGEM
AFLTVRWNEE DFEFLAFNDS WKACKPMLSV GAPVACEVIK LDGDSANLST VVRLDWMD
//
