ID B5MCZ4_HUMAN Unreviewed; 230 AA.
AC B5MCZ4;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Kelch repeat and BTB domain containing 12 {ECO:0000313|Ensembl:ENSP00000385830.3};
GN Name=KBTBD12 {ECO:0000313|Ensembl:ENSP00000385830.3};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000385830.3, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000385830.3, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000385830.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC011311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; B5MCZ4; -.
DR SMR; B5MCZ4; -.
DR MassIVE; B5MCZ4; -.
DR PeptideAtlas; B5MCZ4; -.
DR Antibodypedia; 52602; 30 antibodies from 11 providers.
DR Ensembl; ENST00000407609.7; ENSP00000385830.3; ENSG00000187715.13.
DR UCSC; uc003ejy.5; human.
DR HGNC; HGNC:25731; KBTBD12.
DR VEuPathDB; HostDB:ENSG00000187715; -.
DR GeneTree; ENSGT00940000156836; -.
DR HOGENOM; CLU_1075826_0_0_1; -.
DR OMA; DYWRDGP; -.
DR ChiTaRS; KBTBD12; human.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000187715; Expressed in tibialis anterior and 119 other cell types or tissues.
DR ExpressionAtlas; B5MCZ4; baseline and differential.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR SMART; SM00612; Kelch; 3.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 1: Evidence at protein level;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B5MCZ4};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 230 AA; 26031 MW; EC96E6985E26BB35 CRC64;
MKIKNQYLIT NCVDKYSVER DNWKRVSPLP LQLACHAVVT VNNKLYVIGG WTPQMDLPDE
EPDRLSNKLL QYDPSQDQWS VRAPMKYSKY RFSTAVVNSE IYVLGGIGCV GQDKGQVRKC
LDVVEIYNPD GDFWREGPPM PSPLLSLRTN STNAGAVDGK LYVCGGFHGA DRHEVISKEI
LELDPWENQW NVVAINVLMH DSYDVCLVAR MNPRDLIPPP SDLVEEGNEH
//
