ID B5RTD0_DEBHA Unreviewed; 1390 AA.
AC B5RTD0;
DT 04-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 04-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=DEHA2C17028p {ECO:0000313|EMBL:CAR65592.1};
GN OrderedLocusNames=DEHA2C17028g {ECO:0000313|EMBL:CAR65592.1};
OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX NCBI_TaxID=284592 {ECO:0000313|EMBL:CAR65592.1, ECO:0000313|Proteomes:UP000000599};
RN [1] {ECO:0000313|EMBL:CAR65592.1, ECO:0000313|Proteomes:UP000000599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC
RC 2968 {ECO:0000313|Proteomes:UP000000599};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
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DR EMBL; CR382135; CAR65592.1; -; Genomic_DNA.
DR RefSeq; XP_002770229.1; XM_002770183.1.
DR STRING; 284592.B5RTD0; -.
DR GeneID; 8998405; -.
DR KEGG; dha:DEHA2C17028g; -.
DR VEuPathDB; FungiDB:DEHA2C17028g; -.
DR eggNOG; KOG1703; Eukaryota.
DR eggNOG; KOG2710; Eukaryota.
DR HOGENOM; CLU_001321_1_0_1; -.
DR InParanoid; B5RTD0; -.
DR OMA; QCSAKFF; -.
DR OrthoDB; 1329523at2759; -.
DR Proteomes; UP000000599; Chromosome C.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09392; LIM2_Lrg1p_like; 1.
DR CDD; cd04397; RhoGAP_fLRG1; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR14963; RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED; 1.
DR PANTHER; PTHR14963:SF1; RHO GTPASE-ACTIVATING PROTEIN CONUNDRUM; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00132; LIM; 3.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000599};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 263..328
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 331..391
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 682..748
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 1093..1303
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 65..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 844..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 985..1014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1356..1390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..864
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 875..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 906..920
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 921..935
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1356..1373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1374..1390
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1390 AA; 157136 MW; 54FC7336750981CB CRC64;
MSNPSDSKNI PTNKKPYKNS HTSPYKLQAS DIYNPNDSPL INKPASKHNG MRLHLRSHSY
GYSNDKKDFA GGGIPAPNYA HNNTPNWKTL IPPMPSYPQP TYKTDKRSYS PSQLQKKSFQ
SQPNTQIPIH VQQAPSHGNS PHARAPQSKP QSDGDHHLSK PNQRHSIAVS PSSEKSNFMG
NASPSPALNQ SHQFHNAPQS PPPRIQNQRS KTQIPQAPIQ EIPPFQRQMS SNIPDLSRES
LDQTDIQSRP SQIRQKSMHK KKKFCKGCGL EITGQFVRAL SSAFHIECFR CSECGNQCSS
KFFPYEMLDE PTGIKYQVAL CEYDYFKKLN LICFNCNNAL RGPYITALGN KYHLEHFKCA
VCQVVFESDE SYYEHEGEIY CHYHYSKLYA THCEGCHSSI VKQFVELFRG GRNQQWHPEC
YMVHKFWNVC ILADSVGLRQ HFNINDSNVS NITIFLNESN LKAELLIAIE QHVENTIMNC
WLTLSGYEET TAACISDMLL NACTSNQSAG LIATGKLILN VEVLFNALDV VQDLCSVVNS
NVTSKSTSPN TSTSIKNTAS SEDLTFLEMD IFQPLRKEPR NISGKIMSYL AILRKSMQTT
LSGSLSTELL AVVTGCAHYL KLLIRIGLNN ALKVNKLQGT TDATDKFLSL MKIYEEFNSS
GDNKVNRELI KSRLSIPTNA TDSCQTCVKS IEKSCIRLDN KRWHTKCFIC YNCSKPIASV
RATISQSAYN ISNSQVYCTE CFNRNDKTFI LGFELVSDLS QLVYLLKIAL YRSKSVMKVE
NKSVSQVRQA SLKSKNMSII DEESAARNAT ADDYSKTLND VTRLRASRQS QKLSNSIKQN
ARKSVILEAP EADKAKRDET NAEGLVDDFE GSNEDIINKP NQTERKASIS SQLSYIQQPE
NDQFNISSRR SKKSLRIKDE PQKQTTNNNL DRTSDLLQNE KSLTLDDIPR IVAAEQAREQ
RPNAFKHHNS LYQKHAPMES VRTIPAASTS NASNRNRTSS KSNNNVDNTS NDVPAADYEI
SSSRLKYYSE LDKSEHFILR HIAVEALIQI SNYNKDELLG LIQTRKLPTF WDKFKFGGTN
DPKKDKHLNV FGVDIQDLTK RYGVDSELGV GPSKLRIPIV VDEIINALRQ KDMSVEGIFR
LNGNIKKLRE LTDQINKNPL KSADISSQTA VQLAALMKKW LRELPNPLLT FNLYDLWISS
QQQKDPLLCK RILQLAYCML PRSHRNLLEV LLYFFSWVAS FAEIDEETGS KMDIHNLATV
ISPNILISKK ASQSDQSPPQ TGDNYFLGIE VVNQLIELHE ELCIIPDDLL LFFEKCKFNE
NKSENISTKE IMNKLEKTSK EIPNFFLSFE TKNNNYNTSA QPNVQTNKIS RGHSKVTNES
HGETSDVQHP
//
