ID B5X1B0_SALSA Unreviewed; 185 AA.
AC B5X1B0;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=p53 apoptosis effector related to PMP-22 {ECO:0000313|EMBL:ACI33091.1, ECO:0000313|RefSeq:NP_001135192.1};
GN Name=PERP {ECO:0000313|EMBL:ACI33091.1};
GN Synonyms=perp {ECO:0000313|RefSeq:NP_001135192.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACI33091.1};
RN [1] {ECO:0000313|EMBL:ACI33091.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33091.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI33091.1, ECO:0000313|RefSeq:NP_001135192.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33091.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACI33091.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33091.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:NP_001135192.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM47 family.
CC {ECO:0000256|ARBA:ARBA00008691}.
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DR EMBL; BT044829; ACI33091.1; -; mRNA.
DR RefSeq; NP_001135192.1; NM_001141720.1.
DR STRING; 8030.ENSSSAP00000002327; -.
DR PaxDb; 8030-ENSSSAP00000002327; -.
DR GeneID; 100196698; -.
DR KEGG; sasa:100196698; -.
DR OMA; PTYFYSS; -.
DR OrthoDB; 4571618at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR Bgee; ENSSSAG00000001209; Expressed in nose and 15 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR015664; P53_induced.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR PANTHER; PTHR14399:SF4; P53 APOPTOSIS EFFECTOR RELATED TO PMP-22; 1.
DR PANTHER; PTHR14399; P53-INDUCED PROTEIN RELATED; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 185 AA; 20829 MW; F027AEB92667D468 CRC64;
MFRCGLAYPR CRWIVPLLLL FAIIFDIIAI AATSGWVEDK DAMSHYASMW SQCRGRNDIW
DCKSLMEFSW AQAVAALMII GLIILIIAFI ISCIALCCTL NISLLPVIGA LLFITVVIQF
IALIIYPVKF NDLIFEGRYD YTWAYGFGWG ATILCIGCGI LFCCLPRYED ELTGLAKTKY
IYTSA
//
