ID B5X210_SALSA Unreviewed; 548 AA.
AC B5X210;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein L-like {ECO:0000313|EMBL:ACI33341.1, ECO:0000313|RefSeq:NP_001133491.1};
GN Name=HNRLL {ECO:0000313|EMBL:ACI33341.1};
GN Synonyms=hnrll {ECO:0000313|RefSeq:NP_001133491.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACI33341.1};
RN [1] {ECO:0000313|EMBL:ACI33341.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33341.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI33341.1, ECO:0000313|RefSeq:NP_001133491.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33341.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACI33341.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33341.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:NP_001133491.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BT045079; ACI33341.1; -; mRNA.
DR RefSeq; NP_001133491.1; NM_001140019.1.
DR GeneID; 100194990; -.
DR KEGG; sasa:100194990; -.
DR CTD; 100194990; -.
DR OMA; HFTSAGQ; -.
DR OrthoDB; 4825346at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR Bgee; ENSSSAG00000072945; Expressed in brain and 14 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR CDD; cd12781; RRM1_hnRPLL; 1.
DR CDD; cd12786; RRM2_hnRPLL; 1.
DR CDD; cd12700; RRM3_hnRPLL; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR034985; hnRPLL_RRM1.
DR InterPro; IPR034986; hnRPLL_RRM2.
DR InterPro; IPR034983; hnRPLL_RRM3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592:SF13; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF13893; RRM_5; 1.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 4.
DR PROSITE; PS50102; RRM; 3.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000313|EMBL:ACI33341.1,
KW ECO:0000313|RefSeq:NP_001133491.1};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 81..155
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 171..249
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 341..415
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..41
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..75
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 60987 MW; 0D7212B2EFCDAFD8 CRC64;
MSLIEEYEEG EYGRAPKRLK TTEVEEGEEL EEGEDSDSES AGLLGDVENV GAEKRPRWTA
TKYGPERRDN GDDSHRIAQS PVVHVRGLCE AVVEADLVEA LEKFGPICYV MMMPFKRQAL
VEFEMVESAD KCVACGSSEA VYIAGQQAFF NYSTSKRITR PTNSDNPNSG NKVLLLSIQN
PLYPITTDVL YTVCNPIGSV MRIVIFKRNG IQAMVEFESI ECAQKAKAAL NGADIYAGCC
TLKIEYARPT RLNVIRNDNE SWDYTKPYLV RRDVSERGKG RQRQAILGEH PSSYGDNGYG
SHCPLLPLPG NSRYKLSSHD IPEVVAYPLP QSSSYNHGSS SVAMVSGLHP AKMNCTRIFN
LFCLYGNIEK VKFMKSVPGT ALVEMGDEYA VDRAITHLNS IKVFGKRLNV CVSKQHAVIP
SQVFELEDGS SSYKDFAMTR NNRFTSQGQA SKNIIQPPSC VLHYYNVPPC ISEDQLLRLC
SEHDVPGFTK FKMFDAKPSS KTISGLLEFD SKTHAVEVLT VLNHYQIRIP NGSNPYTLKL
CFSTSSHL
//
