ID B5X2T0_SALSA Unreviewed; 529 AA.
AC B5X2T0;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Major facilitator superfamily domain-containing protein 2 {ECO:0000313|EMBL:ACI33611.1, ECO:0000313|RefSeq:XP_013989937.1, ECO:0000313|RefSeq:XP_013989938.1};
GN Name=MFSD2 {ECO:0000313|EMBL:ACI33611.1};
GN Synonyms=mfsd2 {ECO:0000313|RefSeq:XP_013989937.1,
GN ECO:0000313|RefSeq:XP_013989938.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACI33611.1};
RN [1] {ECO:0000313|EMBL:ACI33611.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33611.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI33611.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33611.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACI33611.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33611.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:XP_013989937.1, ECO:0000313|RefSeq:XP_013989938.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_013989937.1,
RC ECO:0000313|RefSeq:XP_013989938.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BT045349; ACI33611.1; -; mRNA.
DR RefSeq; XP_013989937.1; XM_014134462.1.
DR RefSeq; XP_013989938.1; XM_014134463.1.
DR STRING; 8030.ENSSSAP00000071836; -.
DR PaxDb; 8030-ENSSSAP00000071836; -.
DR Ensembl; ENSSSAT00000105044; ENSSSAP00000071836; ENSSSAG00000063720.
DR OrthoDB; 6761at2759; -.
DR Proteomes; UP000087266; Chromosome ssa13.
DR Bgee; ENSSSAG00000063720; Expressed in head kidney and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11328:SF31; SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 ISOFORM X1-RELATED; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 58..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 529 AA; 58674 MW; C7245B7EAA6B1604 CRC64;
MAHTTVLSDG SQYENKNELV TTKDGNATLK ARGIPFSRKI SYAVGGMPYQ MTANAKGFFL
QIFLLDVVQM GAFYASLILF LGRAWDAITD PLVGYMVTKS GRTRIGKLIP WIVFSMPLGV
LAYIMMWFTP QESMSPSSSF FWFFIWSCLF DAFMTCYHVP YSSLNMFLGG DQKDRDSATG
YRMGMEVFAT LAGATIQGQI VGVYHAKSAQ DCSQLNYSEA SLRNISSPLI QNFSSPLTDT
LQNTRRAYVL AALVLGGIYF LCCVVLFLGV REQLAPLSTL DRIRMPYLAG MKMVVGHTPY
VNLVFGFLFA SLAFQMAQGN FALFCTHAAG LGAYFQHLVL ILLTAATLSI PLWQTLLLRL
GKKTTLYIGL CMYAPALVVI ASIQSNLPVF IIMSIISGSS LSALYLLPWS MLPDVVDDFK
VKNTTSTDLE PMFYSCYVFF NKFGGGMSVG ISTLALHFAG YKPGACRQNP AVITALRVLF
APVPVVLLFI GLVLFYFYPI NEERRCQIQR ELQKAEKVDG FQVMEAVRL
//
