ID B5X2U2_SALSA Unreviewed; 395 AA.
AC B5X2U2;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Interleukin-13 receptor alpha-2 chain {ECO:0000313|EMBL:ACI33623.1, ECO:0000313|RefSeq:NP_001133641.1};
GN Name=I13R2 {ECO:0000313|EMBL:ACI33623.1};
GN Synonyms=i13r2 {ECO:0000313|RefSeq:NP_001133641.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACI33623.1};
RN [1] {ECO:0000313|EMBL:ACI33623.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33623.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI33623.1, ECO:0000313|RefSeq:NP_001133641.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33623.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACI33623.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI33623.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:NP_001133641.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; BT045361; ACI33623.1; -; mRNA.
DR RefSeq; NP_001133641.1; NM_001140169.1.
DR STRING; 8030.ENSSSAP00000119534; -.
DR PaxDb; 8030-ENSSSAP00000119534; -.
DR GeneID; 100195140; -.
DR KEGG; sasa:100195140; -.
DR CTD; 3597; -.
DR OrthoDB; 3986906at2759; -.
DR Proteomes; UP000087266; Chromosome ssa07.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015321; TypeI_recpt_CBD.
DR PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23037:SF41; CYTOKINE RECEPTOR-LIKE FACTOR 2-RELATED; 1.
DR Pfam; PF09240; IL6Ra-bind; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:ACI33623.1, ECO:0000313|RefSeq:NP_001133641.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001133641.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..395
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001133641.1"
FT /id="PRO_5009732172"
FT TRANSMEM 312..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 126..196
FT /note="Type I cytokine receptor cytokine-binding"
FT /evidence="ECO:0000259|Pfam:PF09240"
SQ SEQUENCE 395 AA; 45519 MW; 0C715F47401459F7 CRC64;
MILKHLAFLL VLRYFINLVA LEVAAEKALS EPLNLSLTWE SEFRIKLSWN APEDLDASCK
VNYMIVTRIG EEKAPLTTTF NLYKEYNVTN DAVNYTVKTN PRDCTGRTIS RPVSIFKPKP
TELVKNFHCS LYSSKAMNCS WLPVNQASDL QLYYGYLDPS HIAACSEYQY RDDQRTGCHL
KGSFLQYDVY FKVNGTLDGL TVQNNFLVVP RYYVKPPAPK VKITEEGQNL ILSWDPPDIG
AVHCWEFVLN YDKCKESVNK EIQSEHVPVK ISYDKRCQYR VKLKAVYAKW CGEGGSDWSE
EEIYGVDDWS TIVFDVVIPA VVFLFLILFI CCFMKHREKL FPTIPHPSLI FKDMLNSNKE
LKSSIGNLYV PVEEEVECKI SLEKDYTLPM MQPDH
//
