ID B5X4G6_SALSA Unreviewed; 446 AA.
AC B5X4G6;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Homeobox protein PKNOX1 {ECO:0000313|EMBL:ACI34197.1, ECO:0000313|RefSeq:NP_001133948.1, ECO:0000313|RefSeq:XP_014005375.1, ECO:0000313|RefSeq:XP_014005376.1};
GN Name=PKNX1 {ECO:0000313|EMBL:ACI34197.1};
GN Synonyms=pknx1 {ECO:0000313|RefSeq:NP_001133948.1,
GN ECO:0000313|RefSeq:XP_014005375.1, ECO:0000313|RefSeq:XP_014005376.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACI34197.1};
RN [1] {ECO:0000313|EMBL:ACI34197.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI34197.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI34197.1, ECO:0000313|RefSeq:NP_001133948.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI34197.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACI34197.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:ACI34197.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:NP_001133948.1, ECO:0000313|RefSeq:XP_014005375.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014005375.1,
RC ECO:0000313|RefSeq:XP_014005376.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/MEIS homeobox family.
CC {ECO:0000256|ARBA:ARBA00009661}.
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DR EMBL; BT045935; ACI34197.1; -; mRNA.
DR RefSeq; NP_001133948.1; NM_001140476.1.
DR RefSeq; XP_014005375.1; XM_014149900.1.
DR RefSeq; XP_014005376.1; XM_014149901.1.
DR STRING; 8030.ENSSSAP00000018993; -.
DR PaxDb; 8030-ENSSSAP00000018993; -.
DR Ensembl; ENSSSAT00000020316; ENSSSAP00000018973; ENSSSAG00000009247.
DR GeneID; 100195447; -.
DR KEGG; sasa:100195447; -.
DR CTD; 100195447; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000087266; Chromosome ssa16.
DR Bgee; ENSSSAG00000009247; Expressed in semen and 15 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR032453; PKNOX/Meis_N.
DR PANTHER; PTHR11850:SF80; HOMEOBOX PROTEIN PKNOX1; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF16493; Meis_PKNOX_N; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000313|RefSeq:NP_001133948.1};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 278..341
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 280..342
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 29..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 417..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..446
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 48828 MW; B29C29048713C3E4 CRC64;
MMEAHSASLD EYPEVDEVLV QMRVGADVEG DPEQSLSEGG AGSPSAMQPQ TPMDTDKQAI
YRHPLFPLLA LLFEKCEQST QSSDCVSSAS FNVDIENFVR SQKKEGKGFF CDDPDVDNLM
VKAIQVLRIH LLELEKVSDL CKDFCSRYIA CLRTKMNSET LLSGGETDSP CSPVQIQTSS
PLTGTLSPQG IVMSASALQQ GNVTLTTVNS AGQVLAGMSP WHTTSTGGTV YQPITVVTPQ
GQVVGQAISP QTIRINNTQL QLQLNQDLSS FFTQEDSSSK SNKRGVLPKS ATNIMRTWLF
QHIGHPYPTE DEKKQLAIQT NLTLLQVNNW FINARRRILQ PMMDSSASDT PKSRKRTPQS
RPTQRFWPMA NNIASAGVGQ EAAMDDDVTM VTMGMSVDEL QTLTSDGATL AMQQVMMGGH
SEEEEGESEE EEEEEEEEGG DMAGLE
//
