ID   B5ZQ07_RHILW            Unreviewed;       816 AA.
AC   B5ZQ07;
DT   25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT   25-NOV-2008, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=FAD dependent oxidoreductase {ECO:0000313|EMBL:ACI56577.1};
DE   Flags: Precursor;
GN   OrderedLocusNames=Rleg2_3310 {ECO:0000313|EMBL:ACI56577.1};
OS   Rhizobium leguminosarum bv. trifolii (strain WSM2304).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=395492 {ECO:0000313|EMBL:ACI56577.1, ECO:0000313|Proteomes:UP000008330};
RN   [1] {ECO:0000313|EMBL:ACI56577.1, ECO:0000313|Proteomes:UP000008330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM2304 {ECO:0000313|EMBL:ACI56577.1,
RC   ECO:0000313|Proteomes:UP000008330};
RX   PubMed=21304679; DOI=10.4056/sigs.44642;
RA   Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R.,
RA   Malfatti S., Kiss H., Lapidus A., Copeland A., Nolan M., Land M.,
RA   Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V., Denton M.,
RA   Yates R., Howieson J.;
RT   "Complete genome sequence of Rhizobium leguminosarum bv trifolii strain
RT   WSM2304, an effective microsymbiont of the South American clover Trifolium
RT   polymorphum.";
RL   Stand. Genomic Sci. 2:66-76(2010).
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; CP001191; ACI56577.1; -; Genomic_DNA.
DR   RefSeq; WP_012558920.1; NC_011369.1.
DR   AlphaFoldDB; B5ZQ07; -.
DR   STRING; 395492.Rleg2_3310; -.
DR   KEGG; rlt:Rleg2_3310; -.
DR   eggNOG; COG0404; Bacteria.
DR   eggNOG; COG0665; Bacteria.
DR   HOGENOM; CLU_007884_11_0_5; -.
DR   Proteomes; UP000008330; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
FT   DOMAIN          9..373
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          376..431
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          434..703
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          728..806
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   816 AA;  91281 MW;  32160BC7C4F4EBE5 CRC64;
     MSNLPSQARV VIIGGGAVGV SALYHLAMAG WTDAVLLEKN ELTAGSTWHA AGNVPTFSSS
     WSIMNMQRYS ASLYRELGAQ VDYPMNYHVT GSIRLGHSNE RLQEFKRVVG MGRYQGMDLD
     ILSPDQIKSK YPFVETHDLI GALHDPHDGD IDPAQLTQAL AKGARDLGAR IFRFCAAIGA
     RRENNEWIVS TPDGDIRCEY VVNAAGYYAR EVGKWFGREV PMMVMSHQYM LFEEIPELAA
     WSKEAGHKLP LLRDVDSSYY LRQEKTGMNL GPYERNCKAH WLTPEDPMPE DFSFQLFPDD
     LERLEWYLND AVERVPILGT AGLSRMINGP IPYTPDGNPL IGPMPGVPNA FEACVFTFGI
     CQAGGAGKVL AEWLTEGQTE WDMWSCDPRR FTRFASDQDY CIAKGMEVYG HEYAMHFPKH
     AWPAGRNRKL SPIHDRIAAL GAQFKSYNGW ERANWYAKSG DDTSEQSTQT WNRAGPWQKR
     IEEECLAVRD AAGILDLPGF SRYRLQGEGA RDWLLGLITG KVPKPGRIGL AYFADDKGRI
     VTEMSVMALE ENLFFLTTAA TAQWHDFAWL QKHLPKDASF TLDDVTDNLA CQILSGPQSR
     AILAEVTDAD LSKPWLTHLS CQIAGRRLQL VRVSFVGELG WELHTEMDDT ATVFDAVWAA
     GGKHGLKPFG MEALDSLRIE KGYRAWKGDL STDYTMLQGG LERFVDWAKP DFKGKAALAR
     EKQQGVTKRF VTLAVEAGEC DAPYMSTLWR DGQLVGETTS GNWGYRVGKS VALGMLRSDL
     AVPGTELEVE IFGDRFKAVV QPDRPLWDPE NERLRA
//