ID   B5ZSY2_RHILW            Unreviewed;       432 AA.
AC   B5ZSY2;
DT   25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT   25-NOV-2008, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=Peptidase M16 domain protein {ECO:0000313|EMBL:ACI53931.1};
GN   OrderedLocusNames=Rleg2_0634 {ECO:0000313|EMBL:ACI53931.1};
OS   Rhizobium leguminosarum bv. trifolii (strain WSM2304).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=395492 {ECO:0000313|EMBL:ACI53931.1, ECO:0000313|Proteomes:UP000008330};
RN   [1] {ECO:0000313|EMBL:ACI53931.1, ECO:0000313|Proteomes:UP000008330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM2304 {ECO:0000313|EMBL:ACI53931.1,
RC   ECO:0000313|Proteomes:UP000008330};
RX   PubMed=21304679; DOI=10.4056/sigs.44642;
RA   Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R.,
RA   Malfatti S., Kiss H., Lapidus A., Copeland A., Nolan M., Land M.,
RA   Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V., Denton M.,
RA   Yates R., Howieson J.;
RT   "Complete genome sequence of Rhizobium leguminosarum bv trifolii strain
RT   WSM2304, an effective microsymbiont of the South American clover Trifolium
RT   polymorphum.";
RL   Stand. Genomic Sci. 2:66-76(2010).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
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DR   EMBL; CP001191; ACI53931.1; -; Genomic_DNA.
DR   RefSeq; WP_012556834.1; NC_011369.1.
DR   AlphaFoldDB; B5ZSY2; -.
DR   STRING; 395492.Rleg2_0634; -.
DR   KEGG; rlt:Rleg2_0634; -.
DR   eggNOG; COG0612; Bacteria.
DR   HOGENOM; CLU_009902_3_0_5; -.
DR   Proteomes; UP000008330; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
FT   DOMAIN          14..160
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          166..339
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   432 AA;  47896 MW;  935C5CBA315B03EB CRC64;
     MTVECTRLKS GLTVVTETMP HLESVALGVW IKSGSRNETA DEHGIAHLLE HMAFKGTGRR
     SARQIAEEIE DVGGEVNAAT STETTSYYAR VLKDHVPLAV DILADILTES AFEEEELERE
     KQVILQEINA ANDTPDDVVF DRFSEVAYRD QTLGRAILGT PETVVSFTPQ QIRGYLGRNY
     TTDRMFVVAT GAVEHDEFVR MVEDRFASLP SEPSAPPVME AARYIGGSVR EPRDLMDAQI
     LLGFEGKPYH ARDFYCSQIL ANILGGGMSS RLFQEVREFR GLCYSVYAFH WGFSDTGIFG
     IHAATGGENL PQLVPVIIDE LHKSADQIHQ KEIERARAQI RAQLLMGQES PASRAGQIAR
     QMMLYGRPIS NMEMMERLEG ITIERLTDLA GRLFYDTVPT LSAIGPLEQL APMEDITASL
     SVPAPKTMQA GR
//