ID B6A9I6_CRYMR Unreviewed; 469 AA.
AC B6A9I6;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Ubiquitin carboxyl-terminal hydrolase family protein {ECO:0000313|EMBL:EEA04877.1};
DE EC=3.1.2.15 {ECO:0000313|EMBL:EEA04877.1};
GN ORFNames=CMU_039440 {ECO:0000313|EMBL:EEA04877.1};
OS Cryptosporidium muris (strain RN66).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=441375 {ECO:0000313|Proteomes:UP000001460};
RN [1] {ECO:0000313|EMBL:EEA04877.1, ECO:0000313|Proteomes:UP000001460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN66 {ECO:0000313|EMBL:EEA04877.1,
RC ECO:0000313|Proteomes:UP000001460};
RA Lorenzi H., Inman J., Miller J., Schobel S., Amedeo P., Caler E.V.,
RA da Silva J.;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS989726; EEA04877.1; -; Genomic_DNA.
DR RefSeq; XP_002139226.1; XM_002139190.1.
DR AlphaFoldDB; B6A9I6; -.
DR STRING; 441375.B6A9I6; -.
DR EnsemblProtists; EEA04877; EEA04877; CMU_039440.
DR GeneID; 6994566; -.
DR VEuPathDB; CryptoDB:CMU_039440; -.
DR eggNOG; KOG2026; Eukaryota.
DR OMA; NKFVAER; -.
DR OrthoDB; 719409at2759; -.
DR Proteomes; UP000001460; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001607; Znf_UBP.
DR PANTHER; PTHR21646:SF16; U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF02148; zf-UBP; 1.
DR SMART; SM00290; ZnF_UBP; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS50271; ZF_UBP; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EEA04877.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001460};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00502}.
FT DOMAIN 3..100
FT /note="UBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50271"
FT DOMAIN 122..466
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
SQ SEQUENCE 469 AA; 53963 MW; 001FA14F1FBBAA0D CRC64;
MEKKCPFLST INRGVLDFDH EKLCSVTLRN EHVYCCLVCG TNFQGRGKGS IAYCHALEMS
HHMFINLHTS RIYCLPDNYE VKEHSLDDIK QYLQPKFDKK LISILDKNCK TYDGSEYIPG
YIGLYNFGKT DALNVVILLL SRIIPLRDFF LYFPIYDSEN FQKISKVPLD KLMFSIIEIV
CKIFNPYNFK GMASPFVLAN TIERKSNSLL PVSTNTEKQS NKTSQDTQFV DPMALLSWII
HYMKKKLSKI KLGYQRCFYQ DKMSKSKNII ASCIEGQVLN CTKINGIEPK SLNLSYDSMK
SVHGSTVNSF ISLSLNIPLP SVLNPSLDSR IPQIAIFDLL QNKFLENSST FQKIWLLPCY
LIVHFKRFSM ESFGLEKNPT IISFPIKNLD LLPYVHPDNL HANPNTKYDL IANIAHKGDT
KSGVFTIQMY HSGRNEWYEI ENLKVEQILP QALLLTTSYI QLYKQSDLH
//
