ID B6AB23_CRYMR Unreviewed; 274 AA.
AC B6AB23;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Transcription factor E2f/dimerisation partner domain-containing protein {ECO:0000313|EMBL:EEA05575.1};
GN ORFNames=CMU_025820 {ECO:0000313|EMBL:EEA05575.1};
OS Cryptosporidium muris (strain RN66).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=441375 {ECO:0000313|Proteomes:UP000001460};
RN [1] {ECO:0000313|EMBL:EEA05575.1, ECO:0000313|Proteomes:UP000001460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN66 {ECO:0000313|EMBL:EEA05575.1,
RC ECO:0000313|Proteomes:UP000001460};
RA Lorenzi H., Inman J., Miller J., Schobel S., Amedeo P., Caler E.V.,
RA da Silva J.;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|RuleBase:RU003796}.
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DR EMBL; DS989727; EEA05575.1; -; Genomic_DNA.
DR RefSeq; XP_002139924.1; XM_002139888.1.
DR AlphaFoldDB; B6AB23; -.
DR STRING; 441375.B6AB23; -.
DR EnsemblProtists; EEA05575; EEA05575; CMU_025820.
DR GeneID; 6995226; -.
DR VEuPathDB; CryptoDB:CMU_025820; -.
DR eggNOG; KOG2829; Eukaryota.
DR OMA; PPCESTV; -.
DR OrthoDB; 1343784at2759; -.
DR Proteomes; UP000001460; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR015648; Transcrpt_fac_DP.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12548; TRANSCRIPTION FACTOR DP; 1.
DR PANTHER; PTHR12548:SF9; TRANSCRIPTION FACTOR DP; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000001460};
KW Transcription {ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 83..165
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT REGION 23..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 274 AA; 30052 MW; BAC064F94E2679CB CRC64;
MNSVTLGGSG GFVPGGYVQH PVAASGGMEH HPGQYSMSQN PSNANTNEQL VPGEHSSLPH
LTMIPPHHLS NTGDYGNTPS QLRNRCKLGV FSHRVCEKVS AIKVASYHEM TEHLINMELG
DGPGRSKNPE AKNIRRRVYD VLNVLLAIGV VRRSVGVGKN LIWAGLDPER PLIDQLVERS
RMDHTGRLSS GPDELRSEEQ ARAEVETAKI AYLTAFEAQV NALQETIRQR LSTCNDKDIV
AAAEYIGVKQ LLQPVQHPHL HSHLNNPNIA IPEE
//
