ID B6AED4_CRYMR Unreviewed; 421 AA.
AC B6AED4;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=U4/U6 small nuclear ribonucleoprotein Prp31, putative {ECO:0000313|EMBL:EEA06551.1};
GN ORFNames=CMU_012250 {ECO:0000313|EMBL:EEA06551.1};
OS Cryptosporidium muris (strain RN66).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=441375 {ECO:0000313|Proteomes:UP000001460};
RN [1] {ECO:0000313|EMBL:EEA06551.1, ECO:0000313|Proteomes:UP000001460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN66 {ECO:0000313|EMBL:EEA06551.1,
RC ECO:0000313|Proteomes:UP000001460};
RA Lorenzi H., Inman J., Miller J., Schobel S., Amedeo P., Caler E.V.,
RA da Silva J.;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the PRP31 family.
CC {ECO:0000256|ARBA:ARBA00005572}.
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DR EMBL; DS989730; EEA06551.1; -; Genomic_DNA.
DR RefSeq; XP_002140900.1; XM_002140864.1.
DR AlphaFoldDB; B6AED4; -.
DR STRING; 441375.B6AED4; -.
DR EnsemblProtists; EEA06551; EEA06551; CMU_012250.
DR GeneID; 6996127; -.
DR VEuPathDB; CryptoDB:CMU_012250; -.
DR eggNOG; KOG2574; Eukaryota.
DR OMA; IGNGPMD; -.
DR OrthoDB; 4493115at2759; -.
DR Proteomes; UP000001460; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IEA:InterPro.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR InterPro; IPR027105; Prp31.
DR InterPro; IPR019175; Prp31_C.
DR PANTHER; PTHR13904; PRE-MRNA SPLICING FACTOR PRP31; 1.
DR PANTHER; PTHR13904:SF0; U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF09785; Prp31_C; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001460};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000313|EMBL:EEA06551.1}; RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 186..308
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 306..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 421 AA; 47747 MW; 53FF6FB46D822E97 CRC64;
MATLSDLFLQ DLADLKQEYS NTNNIEIQKS QEDKDKDELE KNLSKVFNTI NNGINIKDEN
NYYRVIEDII HTLGNIDKII EILHKNVINL YRPKFGELSS IIINPIQYLE VVKRCIHVSD
ITQVQFNDIL PNSIAMTISI AASTNTNANI SNDTCINIEN LIDDAFSLFK KKNELLKFVE
LEMDKIAPNL SSLVNPNLAA MLICSTNGLR NLAEMPSQNI MLLGSDRKSR KYGLYTTGVL
RIELQQSYLS KCDIVLGVPE LFKKKALRLL SSKCSLCARL DLAKSNKDGK YGKNWRDYII
KILNKSQESP PPPLKKPLPI PEELPKSRRG GRRIRKIKEK SKMSKYSKDM NRMIFGEPEE
EYMVEGESVG LGVLSSENIG KMRSILPIKN KSKYNNDTQL NNNVNGTSTS ISFTPYQGMQ
L
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