ID B6AGG6_CRYMR Unreviewed; 1042 AA.
AC B6AGG6;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Importin-beta N-terminal domain-containing protein {ECO:0000313|EMBL:EEA07307.1};
GN ORFNames=CMU_001780 {ECO:0000313|EMBL:EEA07307.1};
OS Cryptosporidium muris (strain RN66).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=441375 {ECO:0000313|Proteomes:UP000001460};
RN [1] {ECO:0000313|EMBL:EEA07307.1, ECO:0000313|Proteomes:UP000001460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN66 {ECO:0000313|EMBL:EEA07307.1,
RC ECO:0000313|Proteomes:UP000001460};
RA Lorenzi H., Inman J., Miller J., Schobel S., Amedeo P., Caler E.V.,
RA da Silva J.;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the XPO2/CSE1 family.
CC {ECO:0000256|ARBA:ARBA00008669}.
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DR EMBL; DS989732; EEA07307.1; -; Genomic_DNA.
DR RefSeq; XP_002141656.1; XM_002141620.1.
DR AlphaFoldDB; B6AGG6; -.
DR STRING; 441375.B6AGG6; -.
DR EnsemblProtists; EEA07307; EEA07307; CMU_001780.
DR GeneID; 6996766; -.
DR VEuPathDB; CryptoDB:CMU_001780; -.
DR eggNOG; KOG1992; Eukaryota.
DR OMA; AENEFLM; -.
DR OrthoDB; 178772at2759; -.
DR Proteomes; UP000001460; Unassembled WGS sequence.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR005043; XPO2_C.
DR InterPro; IPR013713; XPO2_central.
DR PANTHER; PTHR10997:SF8; EXPORTIN-2; 1.
DR PANTHER; PTHR10997; IMPORTIN-7, 8, 11; 1.
DR Pfam; PF03378; CAS_CSE1; 1.
DR Pfam; PF08506; Cse1; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001460}.
FT DOMAIN 23..96
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1042 AA; 119671 MW; C8432CB749BFC41E CRC64;
MLPEIVSLLN SSISTNPIEV RTAEASLTSK EAQDGFIETL ILIISKGDID ISIRQIACIY
LKNNIKKRWD IDCMNGGVKQ NNRNFIKENI IKMYINTPNI VQTQVAEILL YISVRDFPNY
WPELLSDIIK CFPGDEYLNE SLLNNYDKLN LYSCTLTMTK LVLDKYRCAE SSNKILTELK
DILQIICIPL YKIFIFSSQA LLSGVVIHKP NNTAILNICL LCCQIFYSLH CCDVPEFFEN
NIQVFMYTFH SLLELQHKDD GSESLFLIFN IKSQICENLR IYSDRYQEPF DPYSRKSLSI
IGILLTNIIA NQYLYENGDV STYCSTLIDE GLRLIGSLAS TQWSDNPFVD KGILEHLIEN
ILIPCTFMSI SDLSSIEETP KEFIYKYLWD INEICDSTSK RSAALGCIRS LGKFYNSQLS
ALLTCHIVKL LENLTDSETI FEWTEFSRNT SQPVKYKINK SEVIREGAIF LFICLSVRSF
SRSSGVTQLQ QDVDLVGFYD QYIKRFSTTS LLRCCSLKYL IVFRNHFPPG VSISLLEEAS
QWIPVSSFIV KMMVLLAFEK LFSQRNLNLS SNAGINSNST STHRITGNQA SSLCLQFLND
VLKPLLEETL YNSSNSTCLM TDSEFVPRCI VRLLSYLGLE GKSFISSIVP AVSAHLKLVT
ENPKNPIFNH FLYELLGICI RNTTDYERNA MDPVFLPILI DILQQNRIEF MAYSLQILAL
RLDTLETKNE FYTNLFVHLL DEPIWRSSVS ILPGIVRLLC SYLRKSSLFG ELIPSNLKQI
FNRFQFCLSH RRFQSNIAFD LLRDALRYLP YESYSNYLPT LITLLLTKCQ EWNRADEIIL
ITQIVGVMFL IIIERSQTSN LPTLIILLEN IQSGLSSLFF NKIVFPNINK AVLTPPLRFL
CIAGITKLIS ENSNTITEEL ILESFKSITV LLGGLINDNN SIERRKDDST LDNLESLWDQ
TNYAQDEYEV NYHRLVTASI NYTDIYPNGG EIAKNFHQNF QQLVMLEDSR NMIKITFNPF
LKKLWDYYQN DPTILELITH IK
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