ID B6AHE6_CRYMR Unreviewed; 1952 AA.
AC B6AHE6;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000313|EMBL:EEA07641.1};
GN ORFNames=CMU_005640 {ECO:0000313|EMBL:EEA07641.1};
OS Cryptosporidium muris (strain RN66).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=441375 {ECO:0000313|Proteomes:UP000001460};
RN [1] {ECO:0000313|EMBL:EEA07641.1, ECO:0000313|Proteomes:UP000001460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN66 {ECO:0000313|EMBL:EEA07641.1,
RC ECO:0000313|Proteomes:UP000001460};
RA Lorenzi H., Inman J., Miller J., Schobel S., Amedeo P., Caler E.V.,
RA da Silva J.;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS989734; EEA07641.1; -; Genomic_DNA.
DR RefSeq; XP_002141990.1; XM_002141954.1.
DR STRING; 441375.B6AHE6; -.
DR EnsemblProtists; EEA07641; EEA07641; CMU_005640.
DR GeneID; 6997113; -.
DR VEuPathDB; CryptoDB:CMU_005640; -.
DR eggNOG; KOG0614; Eukaryota.
DR OMA; WIDIDAF; -.
DR OrthoDB; 200682at2759; -.
DR Proteomes; UP000001460; Unassembled WGS sequence.
DR CDD; cd00038; CAP_ED; 4.
DR Gene3D; 2.60.120.10; Jelly Rolls; 4.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR11635; CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN; 1.
DR PANTHER; PTHR11635:SF152; CAMP-DEPENDENT PROTEIN KINASE TYPE II REGULATORY SUBUNIT; 1.
DR Pfam; PF00027; cNMP_binding; 2.
DR SMART; SM00100; cNMP; 4.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 4.
DR PROSITE; PS50042; CNMP_BINDING_3; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000001460}.
FT DOMAIN 1063..1133
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 1189..1310
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 1677..1780
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 1843..1928
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 536..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1339..1390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 235..262
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 536..558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..583
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..611
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..633
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..678
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1339..1372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1373..1390
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1952 AA; 223246 MW; 7F4D5364B0BA81D5 CRC64;
MFEKMKEIRE KRLSSGIIMK HSKEEDQNDA SIDTNKVEDR SNCILNPMDI DAKQDIERRT
QQFLRSRVLK SGINPYAGYS ISNNIYEATN NNKKFGTNRI RVEDQWITSG MIPGDSMTDL
PPQYYSWRKR ELLNSLSPDI QLRKNLLNES ISRIKSIQDK QVDQCSREGE SDDDICKAEN
SAKLFAPPLV MPNIKLSSRK HHVEHTKNIV NSNLIADLVT QQIQEHLENI VVDKQSELEK
KIETLTNQIK TLESKATDYV GKQIKLAMES VKTPKSSLPS VALTPSQQNS TKKPLLSIIK
STISFVDTVD KDTIDIHQSK ILNKPRNLPI ETQKKLGKAP KEEHVPDLIS VKFSHYVTLF
SHHILKNFKS LAAAFKAMRP DSKKEVSKKR FLAFVELNKI PGNDLDHENL YKEICKPKNV
LTVVSLYRNL NPLNNNESWT IEDFANTLFD IYDGDINLAL SALPSNGEFI KVDSFVEFAV
NNLGIKPELA NNIWKNYFDS NNSRCLISVA IKKIINALSL PPETLLKVDK AEFSDSESVN
PSVSSKELES GLQSQDSEQV SEKDQDSASE KNKKYDEDYS SSEISKISDT SSSDQSDSEL
GNSTSGFAGR IGKSYQNDYS PPKEDDTKKD KYDNNNNNNN NNNKENKNER SSARSLLSNS
EAEKKLEKEV DDDRTYNKTS FEVNNSTETQ EQIKDRNTVE QSVSDSENYS KGSSDNESDE
ENNKEKQNFK KGTDPIEKKG EVEGEQTTRN IDNRKDLGNE IITKASFEIV KSDTSVSNNK
DLTVQKKSSI LPDTARVEPL EPAKVNGGSS TIRTSESLNP RVEQYKTQEI LRREAIPLGL
DPTDEILPLD ERFRKRVLDK YTTVAAAYLK ICGGKEIKPN VNITIFGYFM ESLNIYLPFT
ESKIFYKKVA YPDKEITIGS MYRYILELDT KEDFEPVEIG KYLSEIYGSV ENAFIAKCLY
NKSTIKIDEF ISVCKESGFS VKVINDLFNS MVDESSDTVE VQDAIQCIEG HITPEEVKKD
EVTRNSQWAL WRISPDRKIP IDPNIKNKEL KLVSKILINN IDYFQKIGKY ELLSLIENYF
MREQLPEGAY VYRSGDLDYS LSVIISGGVN SVEALWYGGE NILKSFGEGE VIGIRMFEKL
TSNETLRTNS ETVLWKLMPN IWFDKFKPKL SVLSESFGEL EDYINEDRVF GTMSDAKKKE
LFHHTIFTKY PCKTRIFKQG DMPKALILVF DGKVNLYVDK DLSLNPSHYR SLEAGSTIGD
MYLINKEPYP YSAYCASDSD FVVIATVESN KALSILDDDI KKKMLALEKK YQDKRPIPIQ
NIPKFPSLSD INKYISNSSK VEDNTQAETN SPENLKGESK STDQPNNNQD NKKTSDMDNK
DKDTKENIVV KEEDENKELE YLHADIQSRI LRRHSSLADT FKYIYKHHVK KPLLKYNWVL
NLFDTNIQPS NDMCRKWPNY CKMFIGYWID IDAFAEYVSE YLQINATFKY IREIYQRLCY
PLKDQLYIGT FYRNFEEVQN LSLRDMNRRL VEIDKGVYNC FTEMAGITPG SSITLDTFIV
VAARAGFTRD EASDIYTKQL DVLHNKLVSL TTLVKLVAGE ITRKEAEDAE SNYGLLNMAQ
DYFGRDNIIP KIVDLNNMKI DEEKFTSKYE DMKFDENKVI EDKNSSILVD FLGVTEPFNV
LHIGQRHWLV AQMEKKEFDR DDKIITQGNP QSPNLFLISG ELTIIQTSFF GYDSEVGSIR
EVAQYGWTEY YSTNQPSSVS VVAKTTSTVY ILSRSYLEKL NLVISNRIEK IRNISALLLR
TPNIRDWPSF VLDKLAKSLK VQIFNEGEHI LDIGPCDKNS LKFYIVAKGT VHVEGVPFED
EEASNSYKLG SGRYFGEWAI INNYNERTCT IIAEGSVALL TVPKHEFKRV ISEVDEYALN
RFKDYGLKLY HFSPRHASRF NSPLRSPKKF DQ
//
