ID   B6AJA3_CRYMR            Unreviewed;       247 AA.
AC   B6AJA3;
DT   25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT   25-NOV-2008, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Phospholipase/carboxylesterase family protein {ECO:0000313|EMBL:EEA08241.1};
DE            EC=3.1.1.1 {ECO:0000313|EMBL:EEA08241.1};
GN   ORFNames=CMU_019840 {ECO:0000313|EMBL:EEA08241.1};
OS   Cryptosporidium muris (strain RN66).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=441375 {ECO:0000313|Proteomes:UP000001460};
RN   [1] {ECO:0000313|EMBL:EEA08241.1, ECO:0000313|Proteomes:UP000001460}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RN66 {ECO:0000313|EMBL:EEA08241.1,
RC   ECO:0000313|Proteomes:UP000001460};
RA   Lorenzi H., Inman J., Miller J., Schobel S., Amedeo P., Caler E.V.,
RA   da Silva J.;
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 2
CC       family. {ECO:0000256|ARBA:ARBA00006499}.
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DR   EMBL; DS989738; EEA08241.1; -; Genomic_DNA.
DR   RefSeq; XP_002142590.1; XM_002142554.1.
DR   AlphaFoldDB; B6AJA3; -.
DR   STRING; 441375.B6AJA3; -.
DR   EnsemblProtists; EEA08241; EEA08241; CMU_019840.
DR   GeneID; 6997717; -.
DR   VEuPathDB; CryptoDB:CMU_019840; -.
DR   eggNOG; KOG2112; Eukaryota.
DR   OrthoDB; 178765at2759; -.
DR   Proteomes; UP000001460; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0106435; F:carboxylesterase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR003140; PLipase/COase/thioEstase.
DR   PANTHER; PTHR10655; LYSOPHOSPHOLIPASE-RELATED; 1.
DR   PANTHER; PTHR10655:SF17; PALMITOYL-PROTEIN HYDROLASE; 1.
DR   Pfam; PF02230; Abhydrolase_2; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EEA08241.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001460};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        55..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..243
FT                   /note="Phospholipase/carboxylesterase/thioesterase"
FT                   /evidence="ECO:0000259|Pfam:PF02230"
SQ   SEQUENCE   247 AA;  28558 MW;  9547DB3D0429B9F5 CRC64;
     MIEKGDGYGG EGYNYVSEYY NSVFIWLHGR GDTADSFLRY IQIFQQYKSL RRTKIILLTA
     PIISLSYLEG YPFRAWFDML KFEPLFPEKP EHLFKTSSRI INIVLKEIEK GIKSSRIGIG
     GFSQGAASSY FISLSSIKCT FGFCIVVGGW LPLINNFCEK KEVELLNNYI TFEVTDDVKK
     NTKFLILHGE SDPRVPLFWS KRCQDIVLSI IKPKNYQNKI YPNIGHTISI RMENDFLEFM
     AKCLEIC
//