ID B6AYL1_9RHOB Unreviewed; 979 AA.
AC B6AYL1;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Sarcosine oxidase, alpha subunit family {ECO:0000313|EMBL:EDZ42222.1};
GN ORFNames=RB2083_1737 {ECO:0000313|EMBL:EDZ42222.1};
OS Rhodobacteraceae bacterium HTCC2083.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=314270 {ECO:0000313|EMBL:EDZ42222.1, ECO:0000313|Proteomes:UP000005746};
RN [1] {ECO:0000313|Proteomes:UP000005746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2083 {ECO:0000313|Proteomes:UP000005746};
RX PubMed=21036993; DOI=10.1128/JB.01268-10;
RA Kang I., Vergin K.L., Oh H.M., Choi A., Giovannoni S.J., Cho J.C.;
RT "Genome sequence of strain HTCC2083, a novel member of the marine clade
RT Roseobacter.";
RL J. Bacteriol. 193:319-320(2011).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; DS995276; EDZ42222.1; -; Genomic_DNA.
DR AlphaFoldDB; B6AYL1; -.
DR STRING; 314270.RB2083_1737; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0446; Bacteria.
DR HOGENOM; CLU_011963_0_0_5; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000005746; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005746}.
FT DOMAIN 494..577
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 593..859
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 885..971
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 979 AA; 104922 MW; D085C4977B58C466 CRC64;
MTQVNRVEGG QIDRNTPLKF KFDGKSYTGH AGDTLASALL ANGVRLMGRS FKYHRPRGPL
SAGSEEPNAI VTLRDGARAE PNTRATTAEL FDGLSARSQN CWPSVKFDAL AVNDAASDFL
AAGFYYKTFM WPAPFWEKVY EPIIRKAAGL GALSMQEDPD EYDKGFRHCD LLIVGAGPSG
LMAALTAGRA GKEVILADED FAMGGRLLSE QIEVGSTSAL DWTTQTIAEL SSLPNVRLMS
RTTVIGAFDH GIYGAVERVS DHLLEPAIGK PRQILWRIYA GKTLLCAGAT ERPIAFENND
RPGIMLASAM RSYVNRWAAT PAQRVAIFTS CDDGHRTAAD LHAKGIKIAA VIDTRADTPM
SMNYEVLAGA QVTNTKGRLG LTVVEVQLAD GSTRTLECGA LGVSGGWNPN VHLTCHQRGR
PTWDGDLSAF VPGGTLPPGM TVAGAASGDL STNGALLSGA NGAAEALGIK AADTPEADDT
PATQSAFWYV EGCKRAWLDQ QNDVTVKDVR LAHQEGFRSV EHLKRYTTLG MATDQGKTSN
MGGLAIMAEI AGKGIPDVGT TIFRPPYTPV AIGALAGRMR GMEFHPTRLT PSHYWAKECG
AVFVEVGNWL RAQWFPIEGE THWRQSVDRE VKATRASVGV CDCTTLGKID VQGADAATFL
NKVYCNPFAK VAVGKTRYGL MLREDGIAMD DGTAARLAED HFVVTTTTAK AGPVYQHMEF
VRQCLMPDAD VQLISTTEAW AQFAVAGPNS RALLQKIVDP EFDISNEAFE FMACANITVC
GGLRARLFRI SFSGELAFEI AVPSRYGDAL MRKLMEEGEE FDVVPYGTEA LGVMRIEKGH
AAGNELNGTT TANNLGMGRM VSKKKDSIGT VLSERAGLNE DDALKLVGVK PLASEDKITA
GGHLMAADGP VDAANDQGYV TSAAYSPEVG SMIGLALIKS GDARMGEKMR LVSPVTDSEV
LVEVTSAHFV DPEGGRQRA
//
