ID B6AZK6_9RHOB Unreviewed; 976 AA.
AC B6AZK6;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE SubName: Full=Sarcosine oxidase, alpha subunit family {ECO:0000313|EMBL:EDZ41083.1};
GN ORFNames=RB2083_597 {ECO:0000313|EMBL:EDZ41083.1};
OS Rhodobacteraceae bacterium HTCC2083.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=314270 {ECO:0000313|EMBL:EDZ41083.1, ECO:0000313|Proteomes:UP000005746};
RN [1] {ECO:0000313|Proteomes:UP000005746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2083 {ECO:0000313|Proteomes:UP000005746};
RX PubMed=21036993; DOI=10.1128/JB.01268-10;
RA Kang I., Vergin K.L., Oh H.M., Choi A., Giovannoni S.J., Cho J.C.;
RT "Genome sequence of strain HTCC2083, a novel member of the marine clade
RT Roseobacter.";
RL J. Bacteriol. 193:319-320(2011).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; DS995276; EDZ41083.1; -; Genomic_DNA.
DR AlphaFoldDB; B6AZK6; -.
DR STRING; 314270.RB2083_597; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0446; Bacteria.
DR HOGENOM; CLU_011963_0_0_5; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000005746; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF03486; HI0933_like; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005746}.
FT DOMAIN 494..578
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 593..856
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 882..968
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 976 AA; 105066 MW; C1952CE279607954 CRC64;
MRIENKGLID RTQPVNFTFD GHHYQGFAGD TVASALLAND QRLMGRSFKY HRPRGVLTAG
SEEPNALVTI KRGQNVEPNV RATVQEIYDG LEVRSQNAWP TLGFDALAVN DLAAPFFSAG
FYYKTFMRPR AFWERVYEPL IRRAAGLGGL SGTSNDVEYE KAFAFCDVLI IGAGPTGLMA
ALEAGRAGAD VILADEDAQA GGRLLGETYE IDGRTGQDWA AAVIAELSSM NNVRIMSRTT
VTGVYDQGTF GALERVTAHT TPRADAPRAC FWRIVAKCSI LAAGALERPI AFQNNDRPGI
MTAGAVRAYL NRWGVTAGRD IVVFGNNDDA HRTALDLSAA GVHVAALVDS RPDVQVSGDF
PVYAGAQICG ASGRQGLESV TIRTQSGTER IASECLAMSG GWNPSVHMTC HMNGRPEWRE
DIASFVPRAG MIPGMVTAGA CNGTFSTHGA LLEGRKAAEK ILVALGKKAI QSDLPEAEDA
PIHISPLWAV GGTGRAWLDF QNDVTVKDVK QAAKENFRSV EHMKRYTTQG MATDQGKNSN
VNALAILADV TGRGIPETGT TTFRPPYTPV SIAAMGAGAE GKGFAPERLV TSHESTVAQG
APMIEAGMWC RPSYFPKEGE TNWRQSCDRE VNMVRSSVGI CDVSTLGKID IQGPDVAAFL
DFVYINTFST LKPGRVRYGL MLREDGTVMD DGTTARLSDT HYVMTTTTAA AGAVMRHLEY
VHQCLRPELD VSMISVTEQW AQFAVAGPKS RELLNELLDA PIDNDSFPFM GCGDVAIGGV
NARLFRISFS GEHAYEIAVP ARYGAALFNA LNEHAAALGG GPYGMEALNV LRIEKGFITH
AEIHGRVTAF DIGMGRMISA KKDCIGQTMA AREGLVGPNR EQLIGLKPIG AVKQLTGGAH
LFEPESEPTR QNSIGYVTSV GFSPTEVSFL GMGFLMNGRA RHGETIKLID HMRGIETLCE
ICDPVFHDPE GGKPRG
//
