ID B6B1V6_9RHOB Unreviewed; 293 AA.
AC B6B1V6;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Dihydrodipicolinate synthase {ECO:0000313|EMBL:EDZ41634.1};
DE EC=4.2.1.52 {ECO:0000313|EMBL:EDZ41634.1};
GN Name=dapA_1 {ECO:0000313|EMBL:EDZ41634.1};
GN ORFNames=RB2083_1149 {ECO:0000313|EMBL:EDZ41634.1};
OS Rhodobacteraceae bacterium HTCC2083.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=314270 {ECO:0000313|EMBL:EDZ41634.1, ECO:0000313|Proteomes:UP000005746};
RN [1] {ECO:0000313|Proteomes:UP000005746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2083 {ECO:0000313|Proteomes:UP000005746};
RX PubMed=21036993; DOI=10.1128/JB.01268-10;
RA Kang I., Vergin K.L., Oh H.M., Choi A., Giovannoni S.J., Cho J.C.;
RT "Genome sequence of strain HTCC2083, a novel member of the marine clade
RT Roseobacter.";
RL J. Bacteriol. 193:319-320(2011).
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; DS995276; EDZ41634.1; -; Genomic_DNA.
DR AlphaFoldDB; B6B1V6; -.
DR STRING; 314270.RB2083_1149; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_049343_5_0_5; -.
DR Proteomes; UP000005746; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF73; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000005746}.
FT ACT_SITE 125
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 153
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 37
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
FT BINDING 194
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 293 AA; 32281 MW; 5F70ADC6055D5DEF CRC64;
MVTPFNGDFT LNKDALERTV EYLIDAGVHG LIVAGTTGEY YAMSMKERVY MMGLCRELIK
ERLPMIVGTG AIRTEESIEY AQQAKANGAD GLLIATPPYA YPNSREIAMH CLAIDRAANL
PAMLYNYPGR MSVNMDDEVL DRLGRSPNFC AIKESSGDIN RVHMLARDYP HIQMSCGMDD
QALEFFAWGA RSWVCAGSNF APHAHIALYQ ACAVEGDFTK GRAIMSAMLP LMRVLEQGGK
FVQCIKHGLT LRGIPAGPPR RPMLALNKDD KRELDQVIRT MDAALAAIEG ESA
//
