ID B6BGG7_SULGG Unreviewed; 207 AA.
AC B6BGG7; H1FYG9;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE RecName: Full=uracil phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00011894};
DE EC=2.4.2.9 {ECO:0000256|ARBA:ARBA00011894};
DE AltName: Full=UMP pyrophosphorylase {ECO:0000256|ARBA:ARBA00031082};
GN Name=upp {ECO:0000313|EMBL:EHP29595.1};
GN ORFNames=SMGD1_1071 {ECO:0000313|EMBL:EHP29595.1};
OS Sulfurimonas gotlandica (strain DSM 19862 / JCM 16533 / GD1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Sulfurimonadaceae; Sulfurimonas.
OX NCBI_TaxID=929558 {ECO:0000313|EMBL:EHP29595.1, ECO:0000313|Proteomes:UP000006431};
RN [1] {ECO:0000313|EMBL:EHP29595.1, ECO:0000313|Proteomes:UP000006431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GD1 {ECO:0000313|EMBL:EHP29595.1,
RC ECO:0000313|Proteomes:UP000006431};
RX PubMed=22203982; DOI=10.1073/pnas.1111262109;
RA Grote J., Schott T., Bruckner C.G., Glockner F.O., Jost G., Teeling H.,
RA Labrenz M., Jurgens K.;
RT "Genome and physiology of a model Epsilonproteobacterium responsible for
RT sulfide detoxification in marine oxygen depletion zones.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:506-510(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage pathway;
CC UMP from uracil: step 1/1. {ECO:0000256|ARBA:ARBA00005180}.
CC -!- SIMILARITY: Belongs to the UPRTase family.
CC {ECO:0000256|ARBA:ARBA00009516}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHP29595.1}.
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DR EMBL; AFRZ01000001; EHP29595.1; -; Genomic_DNA.
DR RefSeq; WP_008336788.1; NZ_DS995286.1.
DR AlphaFoldDB; B6BGG7; -.
DR STRING; 929558.SMGD1_1071; -.
DR PATRIC; fig|929558.5.peg.1066; -.
DR eggNOG; COG0035; Bacteria.
DR HOGENOM; CLU_067096_2_0_7; -.
DR OrthoDB; 9781675at2; -.
DR UniPathway; UPA00574; UER00636.
DR Proteomes; UP000006431; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0004845; F:uracil phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
DR GO; GO:0006223; P:uracil salvage; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR005765; Ura_phspho_trans.
DR NCBIfam; TIGR01091; upp; 1.
DR PANTHER; PTHR32315; ADENINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR32315:SF4; URACIL PHOSPHORIBOSYLTRANSFERASE, CHLOROPLASTIC; 1.
DR Pfam; PF14681; UPRTase; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
PE 3: Inferred from homology;
KW Allosteric enzyme {ECO:0000256|ARBA:ARBA00022533};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:EHP29595.1}; GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006431};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EHP29595.1}.
SQ SEQUENCE 207 AA; 23225 MW; C4D879C22D54B10D CRC64;
MIHELTNPLT KTLVTHLRDQ RRDAVRFRHT IAELTKQLVY EAFHDFPLLD RTVITWTGEL
SCKTIDEESI VVVTVLRAGM PMLDSVMELL PDAHAGFLAM KRDETTHESV LYYDRLPDCK
GKTILLVDPM VATGGSMIDA LELIKSRKPS RIITLNIIGS PEGLDVVKSA YPEIDIYIAQ
IDEKLNEDKY IIPGLGDAGD RSYNTVG
//
