ID B6BGK4_SULGG Unreviewed; 1036 AA.
AC B6BGK4; H1FYT6;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Efflux system, integral membrane protein {ECO:0000313|EMBL:EHP29631.1};
GN ORFNames=SMGD1_1107 {ECO:0000313|EMBL:EHP29631.1};
OS Sulfurimonas gotlandica (strain DSM 19862 / JCM 16533 / GD1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Sulfurimonadaceae; Sulfurimonas.
OX NCBI_TaxID=929558 {ECO:0000313|EMBL:EHP29631.1, ECO:0000313|Proteomes:UP000006431};
RN [1] {ECO:0000313|EMBL:EHP29631.1, ECO:0000313|Proteomes:UP000006431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GD1 {ECO:0000313|EMBL:EHP29631.1,
RC ECO:0000313|Proteomes:UP000006431};
RX PubMed=22203982; DOI=10.1073/pnas.1111262109;
RA Grote J., Schott T., Bruckner C.G., Glockner F.O., Jost G., Teeling H.,
RA Labrenz M., Jurgens K.;
RT "Genome and physiology of a model Epsilonproteobacterium responsible for
RT sulfide detoxification in marine oxygen depletion zones.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:506-510(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHP29631.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFRZ01000001; EHP29631.1; -; Genomic_DNA.
DR RefSeq; WP_008335811.1; NZ_DS995286.1.
DR AlphaFoldDB; B6BGK4; -.
DR STRING; 929558.SMGD1_1107; -.
DR PATRIC; fig|929558.5.peg.1102; -.
DR eggNOG; COG3696; Bacteria.
DR HOGENOM; CLU_002755_1_2_7; -.
DR OrthoDB; 9798415at2; -.
DR Proteomes; UP000006431; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF19; CATION EFFLUX SYSTEM PROTEIN CUSA; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006431};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 864..883
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 890..910
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 916..940
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 976..995
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1007..1030
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1036 AA; 115071 MW; 5D8DDB38F55F7FBA CRC64;
MIESIISFSI RNKFLILMAT LFLTFASYWA LKNTPLDAIP DLSPPQVIVK LNWAGQSPEI
IEDQGTYPLV SQFLAIANIE TVRGFSTYEN ALIYIIFKEG TDLYWARTRV LEQLASVQSS
LPESMEVNLG PDASGVGWVY EYALTSKTKN LSELRTLQDY YYKYALLGVD GVSEVASIGG
FVPTYQVSVS NDTLTRYNLS IQDVAKTLKE NNNDTGGRIV IQNGFEWMIQ AKGYLKDLDD
IRSLVVTSKA NIPVTIGDIG RVELVPGSRR GMADLNGEGE VVGGIVMVRY GEDVYATIKR
IEKKMSELQV DGVEVIETYN RSELIEKAVD TLKFTLIEEI VIVIIIITLF LMHLRSSIIV
LVALPLTIGA TFLLMKVFGI DSNIMSLGGI AIAIGAMVDA TIVMIENAHK TIIKEEEKKG
ESLTKQERYD AIASSSKVVG RPIFFALALV VVSFLPIFAL SGQEGLLFTP LAFTKTFAMT
AGAIISITLV PVLMLFFVKG KILSENKNPL NRFFVWLYHP IIIYGLKLKY IVILAAVVAL
GFMYPLYNGL KWEFMPPLNE QSLMYMPVTP YGISVDQSKI LTQKTDAIIK SFPEVDTVFG
KGGRANSATD PAPLGMIETI ITFKPQIEWR EGMTHEKLMA KLEEALQVPG LVNSWTYPIR
GRIDMLLSGI RTPLGIKLYG KDAAGLQKYA LEIESKLRTY DKTQSVFADQ ASAGYYLDIE
IDEKELARFK ISKNYLLDYV ASGVGGMKVS TMYKGIERYP IALRFEENER RSIESIRELQ
VKTSLGFVPL GNFAKVAYRE SASVIKSEMA SPVTFIYITP QVGVSATEYK KEAKVLLDDI
KLPAGYYIDW AGQSEYLDSA MQKIVWIVPA VLIVILILIY FALKELVPTF IVFFSLPFAL
LGGLIYIDML NFNMSIAVIV GFLALLGIAA ETAIVMIVYL QEAVNDAKEK FATNFGHLEL
RDAIYEGAVK RVRPKLMTVF STLAGLLPIM YINGVGSEVM QRIAAPMIGG LISSAVLSLV
IIPILFEIYA KWGMRK
//
