ID B6BMZ0_SULGG Unreviewed; 1010 AA.
AC B6BMZ0; H1FY39;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 81.
DE SubName: Full=DNA mismatch repair protein MutS {ECO:0000313|EMBL:EHP30735.1};
GN Name=mutS {ECO:0000313|EMBL:EHP30735.1};
GN ORFNames=SMGD1_2212 {ECO:0000313|EMBL:EHP30735.1};
OS Sulfurimonas gotlandica (strain DSM 19862 / JCM 16533 / GD1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Sulfurimonadaceae; Sulfurimonas.
OX NCBI_TaxID=929558 {ECO:0000313|EMBL:EHP30735.1, ECO:0000313|Proteomes:UP000006431};
RN [1] {ECO:0000313|EMBL:EHP30735.1, ECO:0000313|Proteomes:UP000006431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GD1 {ECO:0000313|EMBL:EHP30735.1,
RC ECO:0000313|Proteomes:UP000006431};
RX PubMed=22203982; DOI=10.1073/pnas.1111262109;
RA Grote J., Schott T., Bruckner C.G., Glockner F.O., Jost G., Teeling H.,
RA Labrenz M., Jurgens K.;
RT "Genome and physiology of a model Epsilonproteobacterium responsible for
RT sulfide detoxification in marine oxygen depletion zones.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:506-510(2012).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHP30735.1}.
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DR EMBL; AFRZ01000001; EHP30735.1; -; Genomic_DNA.
DR RefSeq; WP_008339479.1; NZ_DS995291.1.
DR AlphaFoldDB; B6BMZ0; -.
DR STRING; 929558.SMGD1_2212; -.
DR PATRIC; fig|929558.5.peg.2203; -.
DR eggNOG; COG0249; Bacteria.
DR eggNOG; COG1403; Bacteria.
DR HOGENOM; CLU_002472_3_1_7; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000006431; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006431}.
FT DOMAIN 323..649
FT /note="DNA mismatch repair protein MutS core"
FT /evidence="ECO:0000259|SMART:SM00533"
FT DOMAIN 688..878
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|SMART:SM00534"
FT REGION 978..1010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 978..1004
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1010 AA; 115689 MW; 61EC98A4E7B22B2D CRC64;
MLSSDVSSIL NNKDKLLTQI YFDLQRYFED KYGSNTVVFM EIGTFFEVYE VNNDDEQVGK
AKEIAELLNI QLTKKNKNII ENSDKNPLLA GVPAVSFERY LSRLIQEQKY TIIVVKQKGN
PPKISRYISQ IVSPGTNFDH IVDNDDNYIA SILVDCYRGI YNVGYSAIDV TTGKTWLYET
HGTSEDPSYA LDEIFNLLNI YRTSEVVISF LDGVQDPKHV VQYLEIAEHY HYSVNNQRPK
VDFQNKLFAE VYQIQSLLSP IEHLDLERNP MITESLAVLV HFVIEHDIHI VQKLNRPNLI
DNRRFMYLGN NALEQVGIIS KDRNEFTLLK MLDKSATAIG RRLLKERLLN PIMEKDELER
RYNLIERVSS HTRFLDETMR GVYDLERLSR RLNLGRLHPF EMNHVFESMV SVKDLMGYVK
KHKIQKTPFH ESELDEFLRD ISKSIDLDVS RRFTNATVDE NFLMSGVDEA VDILVEQNAT
MLIAFEDIMS KIEALLEASN ASSSSRLVSL GVLEKEGYYI SLSKNRYSMI ESEFKNHEDF
QEFNVKKLTN SVKITSPFTD TLSDKIMKNR RKIVVLVKDR YIQLQALYER RYSLLFSRVI
AYVADLDVGV SSSKVSQEYK HSRPMIVDVK DDENFMQVMQ LRHPLIEVQE RGGIYVPNDI
VMGNRDYMDL PHPETVMLEV GVHDGHEING VLLYGINSSG KSSLMKSIGI AVLMAQSGFF
VSAAVMKFSL FDSIFTRIVS KDNLAKGLST FAVEMLELKN IFNRATVRSL ILGDEISHGT
ETLSGVAIVS SAIIKLSRLR SLFLFATHLH QLSTMKEITT LNNVVDLHLS VEYDEEKDAL
LFNRVLQSGS GSSIYGLEFA KSLHMDAEFL DIANKIRKRL ANDFDELELL VKKKKSKYNK
DLYVTKCVIC GAVAEDVHHI SQRSLADKAG FIGHFHKDNK HNLVPLCKEH HNDIHNGKLR
VDGFMMTSNG LELQFEEQMK KPKTAEVNEP EINEPKAKDA SDEFVLDDWD
//
