GenomeNet

Database: UniProt
Entry: B6EGC4_ALISL
LinkDB: B6EGC4_ALISL
Original site: B6EGC4_ALISL 
ID   B6EGC4_ALISL            Unreviewed;       377 AA.
AC   B6EGC4;
DT   25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT   25-NOV-2008, sequence version 1.
DT   08-MAY-2019, entry version 67.
DE   RecName: Full=T-protein {ECO:0000256|PIRNR:PIRNR001499};
GN   Name=tyrA {ECO:0000313|EMBL:CAQ78339.1};
GN   OrderedLocusNames=VSAL_I0654 {ECO:0000313|EMBL:CAQ78339.1};
OS   Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain
OS   LFI1238)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Aliivibrio.
OX   NCBI_TaxID=316275 {ECO:0000313|EMBL:CAQ78339.1, ECO:0000313|Proteomes:UP000001730};
RN   [1] {ECO:0000313|EMBL:CAQ78339.1, ECO:0000313|Proteomes:UP000001730}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LFI1238 {ECO:0000313|EMBL:CAQ78339.1,
RC   ECO:0000313|Proteomes:UP000001730};
RX   PubMed=19099551; DOI=10.1186/1471-2164-9-616;
RA   Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S.,
RA   Bason N., Churcher C., Harris D., Norbertczak H., Quail M.A.,
RA   Sanders S., Thurston S., Parkhill J., Willassen N.P., Thomson N.R.;
RT   "The genome sequence of the fish pathogen Aliivibrio salmonicida
RT   strain LFI1238 shows extensive evidence of gene decay.";
RL   BMC Genomics 9:616-616(2008).
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tyrosine biosynthesis; (4-
CC       hydroxyphenyl)pyruvate from prephenate (NAD(+) route): step 1/1.
CC       {ECO:0000256|PIRNR:PIRNR001499}.
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; prephenate
CC       biosynthesis; prephenate from chorismate: step 1/1.
CC       {ECO:0000256|PIRNR:PIRNR001499}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR001499}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; FM178379; CAQ78339.1; -; Genomic_DNA.
DR   RefSeq; WP_012549461.1; NC_011312.1.
DR   STRING; 316275.VSAL_I0654; -.
DR   EnsemblBacteria; CAQ78339; CAQ78339; VSAL_I0654.
DR   KEGG; vsa:VSAL_I0654; -.
DR   eggNOG; ENOG4105EHE; Bacteria.
DR   eggNOG; COG0287; LUCA.
DR   eggNOG; COG1605; LUCA.
DR   HOGENOM; HOG000275725; -.
DR   KO; K14187; -.
DR   OMA; QIQIWGA; -.
DR   OrthoDB; 533829at2; -.
DR   UniPathway; UPA00120; UER00203.
DR   UniPathway; UPA00122; UER00961.
DR   Proteomes; UP000001730; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0046417; P:chorismate metabolic process; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.59.10; -; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR008244; Chor_mut/prephenate_DH_T.
DR   InterPro; IPR036263; Chorismate_II_sf.
DR   InterPro; IPR036979; CM_dom_sf.
DR   InterPro; IPR002701; CM_II_prokaryot.
DR   InterPro; IPR011277; CM_T.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003099; Prephen_DH.
DR   Pfam; PF01817; CM_2; 1.
DR   Pfam; PF02153; PDH; 1.
DR   PIRSF; PIRSF001499; Chor_mut_pdh_Tpr; 1.
DR   SMART; SM00830; CM_2; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF48600; SSF48600; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01799; CM_T; 1.
DR   PROSITE; PS51168; CHORISMATE_MUT_2; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001499};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001499};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001730};
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR001499};
KW   Isomerase {ECO:0000256|PIRNR:PIRNR001499};
KW   NAD {ECO:0000256|PIRNR:PIRNR001499};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR001499,
KW   ECO:0000313|EMBL:CAQ78339.1};
KW   Tyrosine biosynthesis {ECO:0000256|PIRNR:PIRNR001499}.
FT   DOMAIN        1     90       Chorismate mutase. {ECO:0000259|PROSITE:
FT                                PS51168}.
FT   DOMAIN       99    361       Prephenate/arogenate dehydrogenase.
FT                                {ECO:0000259|PROSITE:PS51176}.
SQ   SEQUENCE   377 AA;  42542 MW;  CF5DB0BB86FD50E4 CRC64;
     MAVELSHLRD KIDAVDKQML DLLAQRLQLV EQVGEVKSAY GLPIYDPSRE AAMLASRREE
     AERKGVPPSL IEDILRRTMR ESYSSENDSG FKCLRPELRP IVIVGGKGQL GGLFAKMFKL
     SGYDVRILGS KDWDNADVIL EGVGMVVVTV PINLTIDVIG KLSMLPDDCI LCDLTSIKQK
     PLEAMMKVHK GPVVGLHPMF GPDVPSLAKQ VIVMCDGRGK DAYSWLKDQF EIWGAIVRDI
     SASEHDKGMT LIQALRHFTS FAYGQHLSKE NPDIEQLLNL SSPIYRLELL MVGRLFAQDP
     NLYADIILSS EENIEMIKRF HQRFGDAILL LENHNRVGFI ESFEEVETWF GDYAEQFLVE
     SKGLLRQAND SIHRERN
//
DBGET integrated database retrieval system