ID   B6GAW7_9ACTN            Unreviewed;       720 AA.
AC   B6GAW7;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   08-NOV-2023, entry version 44.
DE   SubName: Full=Glutamate--ammonia ligase, catalytic domain protein {ECO:0000313|EMBL:EEA90643.1};
DE            EC=6.3.1.2 {ECO:0000313|EMBL:EEA90643.1};
GN   Name=glnA {ECO:0000313|EMBL:EEA90643.1};
GN   ORFNames=COLSTE_01217 {ECO:0000313|EMBL:EEA90643.1};
OS   Collinsella stercoris DSM 13279.
OC   Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales;
OC   Coriobacteriaceae; Collinsella.
OX   NCBI_TaxID=445975 {ECO:0000313|EMBL:EEA90643.1, ECO:0000313|Proteomes:UP000003560};
RN   [1] {ECO:0000313|EMBL:EEA90643.1, ECO:0000313|Proteomes:UP000003560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13279 {ECO:0000313|EMBL:EEA90643.1,
RC   ECO:0000313|Proteomes:UP000003560};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Collinsella stercoris (DSM 13279).";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEA90643.1, ECO:0000313|Proteomes:UP000003560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13279 {ECO:0000313|EMBL:EEA90643.1,
RC   ECO:0000313|Proteomes:UP000003560};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEA90643.1}.
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DR   EMBL; ABXJ01000068; EEA90643.1; -; Genomic_DNA.
DR   AlphaFoldDB; B6GAW7; -.
DR   STRING; 445975.COLSTE_01217; -.
DR   eggNOG; COG3968; Bacteria.
DR   HOGENOM; CLU_024307_0_0_11; -.
DR   Proteomes; UP000003560; Unassembled WGS sequence.
DR   GO; GO:0004356; F:glutamine synthetase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.20.120.1560; -; 1.
DR   Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR   InterPro; IPR040577; Gln-synt_C.
DR   InterPro; IPR008147; Gln_synt_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   InterPro; IPR008146; Gln_synth_cat_dom.
DR   InterPro; IPR027303; Gln_synth_gly_rich_site.
DR   InterPro; IPR022147; GSIII_N.
DR   PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR   PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR   Pfam; PF00120; Gln-synt_C; 1.
DR   Pfam; PF18318; Gln-synt_C-ter; 1.
DR   Pfam; PF12437; GSIII_N; 1.
DR   SMART; SM01230; Gln-synt_C; 1.
DR   SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR   PROSITE; PS00181; GLNA_ATP; 1.
DR   PROSITE; PS51986; GS_BETA_GRASP; 1.
DR   PROSITE; PS51987; GS_CATALYTIC; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000313|EMBL:EEA90643.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003560}.
FT   DOMAIN          86..175
FT                   /note="GS beta-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS51986"
FT   DOMAIN          180..610
FT                   /note="GS catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51987"
SQ   SEQUENCE   720 AA;  79457 MW;  07954FF27A4A663F CRC64;
     MAYRLQSSTS TSVARSDAPR REHLMADLTD RFGTMVFSED VMKKWLPKDV YKKLAATIEE
     GQPLDLDVAN AVAHAMKEWA IAHGATHYAH WFQPLSGITS EKHDSFLEPN HDGTAITKFS
     GKALIKGEPD ASSFPNGGLR ATFEARGYTA WDATSPAFIK DDVLCIPTAF CSYTGEALDK
     KTPLLRSMTA LDEQAKRVLA LFGKHPKRVV PSVGDEQEYF LIKKDAYRKR RDLVICGRTL
     FGAAPCKGQE LEEHYFGAIR PTVSAYMKDL DNELWALGIP AKTKHNEVAP CQHELAPVYS
     ELNEAVDNNL LMMEKMKLIA SRHDLVCLLH EKPFEGINGS GKHNNWSLGT ADENLLDPGD
     TPLENLQFVV FLTAVIEAVD KYQDLLRASV ASCGNDHRLG ANEAPPAIMS IFLGDQLTEV
     VEMLMDGETS VHATTDTLTF GTVLLPNLEQ DNTDRNRTSP FAFTGNKFEF RAVGSEANVS
     DANLVLDCAV AQALRDFADA LEGTPEADFQ EAALAYCAEH LREHRRILFS GDGYSEAWEK
     EAESRGLCNF RTAADALPAF VAEKNLALFQ ELGVLSEAEA VCRYEVKLEK YNKLMNIEAT
     TMIREARRTY RPVITAYATK VAKGLEAIRA AGAEAAMQCE QNTLNKLCNG ITDINEAIKA
     LDAVHVKAES MADGQEQANC YAHEVAPAMA DLRAAVDAME EIVAADYWPV PTYDDVLFYV
//