ID B6GXL9_PENRW Unreviewed; 612 AA.
AC B6GXL9;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=Putative transferase CAF17, mitochondrial {ECO:0000256|ARBA:ARBA00018540};
DE AltName: Full=Putative transferase caf17, mitochondrial {ECO:0000256|ARBA:ARBA00016916};
GN ORFNames=Pc12g04350 {ECO:0000313|EMBL:CAP80062.1}, PCH_Pc12g04350
GN {ECO:0000313|EMBL:CAP80062.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP80062.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP80062.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. TrmE GTPase family.
CC {ECO:0000256|ARBA:ARBA00011043}.
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DR EMBL; AM920427; CAP80062.1; -; Genomic_DNA.
DR RefSeq; XP_002557304.1; XM_002557258.1.
DR AlphaFoldDB; B6GXL9; -.
DR STRING; 500485.B6GXL9; -.
DR GeneID; 8311828; -.
DR KEGG; pcs:Pc12g04350; -.
DR VEuPathDB; FungiDB:PCH_Pc12g04350; -.
DR eggNOG; KOG1191; Eukaryota.
DR HOGENOM; CLU_019624_3_0_1; -.
DR OMA; IRGYLCT; -.
DR OrthoDB; 5478664at2759; -.
DR BioCyc; PCHR:PC12G04350-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c12.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR CDD; cd04164; trmE; 1.
DR CDD; cd14858; TrmE_N; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.430; tRNA modification GTPase MnmE domain 2; 1.
DR HAMAP; MF_00379; GTPase_MnmE; 1.
DR InterPro; IPR031168; G_TrmE.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR018948; GTP-bd_TrmE_N.
DR InterPro; IPR004520; GTPase_MnmE.
DR InterPro; IPR027368; MnmE_dom2.
DR InterPro; IPR025867; MnmE_helical.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42714; TRNA MODIFICATION GTPASE GTPBP3; 1.
DR PANTHER; PTHR42714:SF2; TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF12631; MnmE_helical; 1.
DR Pfam; PF10396; TrmE_N; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF116878; TrmE connector domain; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 68..194
FT /note="GTP-binding protein TrmE N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10396"
FT DOMAIN 197..609
FT /note="MnmE helical"
FT /evidence="ECO:0000259|Pfam:PF12631"
FT DOMAIN 296..394
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
FT REGION 35..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 66072 MW; A6100665BD254B82 CRC64;
MRASRRVLRW ASPFSSSTSQ PWQTISNKSY IRRHGFLSES PGPRRPPGQA RAFSSTRPTR
FMLDGDSTIY ALSTAIGRAA IAVVRVSGPA CASIYKSLCP NHPLPKARYA VLRTLYDPTQ
PPTPNTILDA GALVLYFPSP RTATGEDILE LHIHGGPAIT KAVLSAIAQT NTPEQTVRYA
EPGEFTRRAF MNDRLSLPQI EALGDTLSAD TEQQRRLAVR GSSDALLNRY ERWRQGLLYA
RGELEALIDF SEDQHFDEST EELVSSVATQ VRALSVQIGF HIANASRGEL LRNGIRVALL
GAPNAGKSSL LNRVVGKEAA IVSTEQGTTR DIVDVGVDLG GWYCKLGDMA GIRAEGSGDG
ETVVIGPVEK EGIRRARERA LESDVVIVVV SLEDTATGVR LFVEPEVLGA VNDCVEAGKC
LIVAINKCDK LHTTLENGVP QSLSDTIHEV FPSVPADRVF AISCEEAKRG ASSLNTTTDP
GNLQVFLRGL ITTFEQIASP LGVDGDGGQY DLSYWEDSLG VTHRQSSNLQ ICLDHLDDFL
SQASSAGCHD DSSREKELGS LASHAESEVD IVTAAEHLRF AADMLAKITG KGESGDVEDV
LGVVFEKFCV GK
//
