ID B6GXQ4_PENRW Unreviewed; 667 AA.
AC B6GXQ4;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Pc12g11750 protein {ECO:0000313|EMBL:CAP80802.1};
GN ORFNames=Pc12g11750 {ECO:0000313|EMBL:CAP80802.1}, PCH_Pc12g11750
GN {ECO:0000313|EMBL:CAP80802.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP80802.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP80802.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; AM920427; CAP80802.1; -; Genomic_DNA.
DR RefSeq; XP_002557992.1; XM_002557946.1.
DR AlphaFoldDB; B6GXQ4; -.
DR STRING; 500485.B6GXQ4; -.
DR CAZy; GH2; Glycoside Hydrolase Family 2.
DR GeneID; 8307568; -.
DR KEGG; pcs:Pc12g11750; -.
DR VEuPathDB; FungiDB:PCH_Pc12g11750; -.
DR eggNOG; KOG2024; Eukaryota.
DR HOGENOM; CLU_009935_2_1_1; -.
DR OMA; LWAPEHP; -.
DR OrthoDB; 19834at2759; -.
DR BioCyc; PCHR:PC12G11750-MONOMER; -.
DR UniPathway; UPA00280; -.
DR Proteomes; UP000000724; Contig Pc00c12.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF3; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT DOMAIN 19..146
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 275..321
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 360..481
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 667 AA; 74467 MW; 1FDC0C1EDF915D30 CRC64;
MTASYPRPDF QRTSLNWNTL DGPWSFTFDD KDEGLSSQWH KNSLEGKPSH QIIVPYAFQT
PASGVNLIEA HEVMWYERRI TDIRTADEKQ KGNRLLLRFG AVDYECSVWV NGVLVGGHRG
GHVPFDIDIS DALADGVTEA RLTLRVRDSP YDMTQPRGKQ FWGPVPESIF YTPSGGIWLS
VWLESVPGMR LLCGSGGTVL RSDDIEGGQL HAKVHVAGRR AGSRAKAEVE VSLGGTSVAK
VDGELPRDKT FIALDLGMKV TDAAVADLKA KNQGLFGVDG VWSRGVALWA PEHPVLYDIT
LRLFGGDGSL VDEVQTTTGM RSLSWQNGDG TFRLNGKPYF QMLFLDQGYW PQTGMTPPSS
EALKTDIQLA QKLGFNGCRK HQKVEDPRFY YWADRMGFLV WGEMANAYEF GTEYIDRFTS
EWTEAVKRDI NHPSIVTWTP LNESWGVSAL KDNIEQRNHV RALYYLTKTL DPSRPINDNC
GWEHVKTDLT TFHDYSDSAE LGAACTNMPA ILEPKGGHEI FTKPIYSGYS GSSIVDKGAQ
HTPGAPVICS EFGGVNIAPP KNSAAAGERD WGYTTASDPA DFLVRFEKLV MAVVKPGHIC
GLVWTQLCDI EQEVNGLYTY DRQEKVPTEK VKAIMDAARD HYYHHVTSHH SKGFRKLLDQ
YKHVVHR
//
