ID B6H2U7_PENRW Unreviewed; 628 AA.
AC B6H2U7;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE SubName: Full=Pc13g15030 protein {ECO:0000313|EMBL:CAP92572.1};
GN ORFNames=Pc13g15030 {ECO:0000313|EMBL:CAP92572.1}, PCH_Pc13g15030
GN {ECO:0000313|EMBL:CAP92572.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP92572.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP92572.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM920428; CAP92572.1; -; Genomic_DNA.
DR RefSeq; XP_002559904.1; XM_002559858.1.
DR AlphaFoldDB; B6H2U7; -.
DR STRING; 500485.B6H2U7; -.
DR GeneID; 8314008; -.
DR KEGG; pcs:Pc13g15030; -.
DR VEuPathDB; FungiDB:PCH_Pc13g15030; -.
DR eggNOG; ENOG502QTER; Eukaryota.
DR HOGENOM; CLU_014123_0_0_1; -.
DR OMA; YQKCIKY; -.
DR OrthoDB; 1387259at2759; -.
DR BioCyc; PCHR:PC13G15030-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c13.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR013122; PKD1_2_channel.
DR PANTHER; PTHR35859; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR PANTHER; PTHR35859:SF1; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR Pfam; PF08016; PKD_channel; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 232..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..510
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 264..462
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
SQ SEQUENCE 628 AA; 72811 MW; CEC0C29FB0762E62 CRC64;
MGHWKNFFTG DPGRTRHRVE VERRRLLPAY AADESDASDA SKEIAKVALR LKYQIEQVVS
CEVEDSALTN PNSRIITDDV IETAKQAGGD DYRACVVYCL LICLRWFKIQ SSVELWDSDL
HGVRAVACEV IAKRIIESEQ NQDYVMRDIL LKRYSIFSEG VETDPANVIE RAVDLHALRI
ISSAPYQKCI QYLWKGWICQ EEGNPTNFVE YSEKSNTGYW VHFHPDRMRT PLYQNVCQIL
FSLIYLAVYT AVINTVNPSG DVDVVEAILY GMTLAFMCDE AIKFWKVGWN YLEFWNAFNS
TLYTILTVSL VLRFIALAHS SSTHNEQRQI YNELSYNFLA FAGPMFWMRM MLYLDSFRFF
GAMFVVLRVM MKESLIFFAL LFVVLAGFFQ AFVGMAQVDA DVPIHRNILQ GMVNSIMQSP
EFDTFQDFAF PFGIILYYVF NFIVMTVLLN ILIALYNSAY EDISGNATDE YMAIFAQKTM
QFVRAPDENV FIPPFNLVEI VFLVAPFEWW LPRETYARLN ELVMGVIYSP LLIVTAWIEN
RQAHRIRWNR RHGEEDDDCA QEWEHVAKEV NFDLDDTWKE HVVETTPDIK VDSCTYELRE
LKEQVMMLTE TVKRLSQELA DKKVGEAS
//
