ID   B6H7U9_PENRW            Unreviewed;       471 AA.
AC   B6H7U9;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=Pc16g07050 protein {ECO:0000313|EMBL:CAP93375.1};
GN   ORFNames=Pc16g07050 {ECO:0000313|EMBL:CAP93375.1}, PCH_Pc16g07050
GN   {ECO:0000313|EMBL:CAP93375.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP93375.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP93375.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC       {ECO:0000256|ARBA:ARBA00009721}.
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DR   EMBL; AM920431; CAP93375.1; -; Genomic_DNA.
DR   RefSeq; XP_002561039.1; XM_002560993.1.
DR   AlphaFoldDB; B6H7U9; -.
DR   STRING; 500485.B6H7U9; -.
DR   GeneID; 8304391; -.
DR   KEGG; pcs:Pc16g07050; -.
DR   VEuPathDB; FungiDB:PCH_Pc16g07050; -.
DR   eggNOG; ENOG502QU0C; Eukaryota.
DR   HOGENOM; CLU_047223_0_0_1; -.
DR   OMA; HVIPTHQ; -.
DR   OrthoDB; 2251964at2759; -.
DR   BioCyc; PCHR:PC16G07050-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c16.
DR   GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR   GO; GO:0009072; P:aromatic amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR011166; Beta-eliminating_lyase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   PIRSF; PIRSF001386; Trpase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT   DOMAIN          48..423
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
SQ   SEQUENCE   471 AA;  52708 MW;  964566133F57ED4C CRC64;
     MSDLPIPQVW RTKMVERVHY STKEQREKWI QAADYNLFNL RSDQIFIDLL TDSGTGAMSD
     QQWAAMMAGD ESYAGSASFD RLQRTVTDIF GLQFLLPVHQ GRAAENALFS VLVKPGDIIP
     ANSHFDTTRA HIEYRKAAAI DCPADVALNT SVDEPFKGNI NLPVLRKILE EDHEKIPFIL
     LTLTCNVTGG QPVSMENITA VKQIATDYGK PLIIDSARFA ENAWFIQQRE HGFRQSSIRE
     ITRQIFLMAD AMLMSAKKDG LVNIGGFMAT RHQDWFDAAT GYVILFEGFR TYGGLSGRDL
     NALAEGLTEV VCAEYLGSRI GQTQRFGQIL IDAGIPIQRP VGGHAVLVNA GSFLPAIPRE
     EYVAQTLAVE LYIEAGVRGV EIGTLLNGRD PSTGRERFAE VEFLRLAIPR RVYSNEQMEY
     VARALVNLYC RRSSFARGLS IVEEKPILRH FTVRLSRKEV RSAETETKVN Q
//