ID B6HC74_PENRW Unreviewed; 357 AA.
AC B6HC74;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE SubName: Full=Pc18g05540 protein {ECO:0000313|EMBL:CAP94778.1};
GN ORFNames=Pc18g05540 {ECO:0000313|EMBL:CAP94778.1}, PCH_Pc18g05540
GN {ECO:0000313|EMBL:CAP94778.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP94778.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP94778.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
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DR EMBL; AM920433; CAP94778.1; -; Genomic_DNA.
DR RefSeq; XP_002562381.1; XM_002562335.1.
DR AlphaFoldDB; B6HC74; -.
DR STRING; 500485.B6HC74; -.
DR GeneID; 8306686; -.
DR KEGG; pcs:Pc18g05540; -.
DR VEuPathDB; FungiDB:PCH_Pc18g05540; -.
DR eggNOG; KOG3857; Eukaryota.
DR HOGENOM; CLU_007207_0_1_1; -.
DR OMA; HAMSHQV; -.
DR OrthoDB; 1591034at2759; -.
DR BioCyc; PCHR:PC18G05540-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c18.
DR GO; GO:0090560; F:2-(3-amino-3-carboxypropyl)histidine synthase activity; IEA:InterPro.
DR GO; GO:0018506; F:maleylacetate reductase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0017183; P:protein histidyl modification to diphthamide; IEA:InterPro.
DR CDD; cd08177; MAR; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR InterPro; IPR016435; DPH1/DPH2.
DR InterPro; IPR034786; MAR.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF105; REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07090)-RELATED; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SFLD; SFLDS00032; Radical_SAM_3-amino-3-carboxyp; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT DOMAIN 10..338
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 357 AA; 38026 MW; D56ED0AE7EE76C5D CRC64;
MDTFEYNPNP GRVVFGSGTL QKLPDEISRL QVKAPLVLST PHQVGQAERV KEVLKGQIAG
IFSEATMHTP TNVTDKAVEY AKARGTDSLI SIGGGSTIGL GKAMSIRTGL PHICIPTTYA
GSEMTPILGE TADGLKKTRS DPKILPGTVI YDVDLTMTLP AAMSATSGVN AIAHAVEALY
ARNTNPIINM MALEGIRALA SSLPEIVENS SSQSARSKAL YGAWLCGTCL GSVGMSIHHK
LCHTLGGSFN LPHAETHTAV LPHAISYNAP SIPEAMKQLA DALPDSNGDA IHGLNILLDK
LKVKRGVKDF GMKEEDIDKA ADIALANAYW NPRPIERAPI RELLRRVWAG EPALANL
//
