ID B6HD92_PENRW Unreviewed; 504 AA.
AC B6HD92;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE RecName: Full=DNA primase {ECO:0000256|RuleBase:RU003514};
DE EC=2.7.7.- {ECO:0000256|RuleBase:RU003514};
GN ORFNames=Pc20g04070 {ECO:0000313|EMBL:CAP85736.1}, PCH_Pc20g04070
GN {ECO:0000313|EMBL:CAP85736.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85736.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP85736.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SIMILARITY: Belongs to the eukaryotic-type primase small subunit
CC family. {ECO:0000256|ARBA:ARBA00009762, ECO:0000256|RuleBase:RU003514}.
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DR EMBL; AM920435; CAP85736.1; -; Genomic_DNA.
DR RefSeq; XP_002562957.1; XM_002562911.1.
DR AlphaFoldDB; B6HD92; -.
DR STRING; 500485.B6HD92; -.
DR GeneID; 8310012; -.
DR KEGG; pcs:Pc20g04070; -.
DR VEuPathDB; FungiDB:PCH_Pc20g04070; -.
DR eggNOG; KOG2851; Eukaryota.
DR HOGENOM; CLU_028288_1_0_1; -.
DR OMA; NVTRGFN; -.
DR OrthoDB; 168741at2759; -.
DR BioCyc; PCHR:PC20G04070-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c20.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003896; F:DNA primase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04860; AE_Prim_S; 1.
DR Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR InterPro; IPR002755; DNA_primase_S.
DR InterPro; IPR014052; DNA_primase_ssu_euk/arc.
DR NCBIfam; TIGR00335; primase_sml; 1.
DR PANTHER; PTHR10536; DNA PRIMASE SMALL SUBUNIT; 1.
DR PANTHER; PTHR10536:SF0; DNA PRIMASE SMALL SUBUNIT; 1.
DR Pfam; PF01896; DNA_primase_S; 1.
DR SUPFAM; SSF56747; Prim-pol domain; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU003514};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU003514};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Primosome {ECO:0000256|ARBA:ARBA00022515, ECO:0000256|RuleBase:RU003514};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003514}.
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..48
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 56908 MW; C313A788A402B70E CRC64;
MPHSVSPGSA QNDDEMPDAP PVETSTETNV RLEDMFNDDD DDDEEFPASG DVKMESPSKE
EPPAPTPSGV DPDIMLAFYQ RLFPFRYLFQ WLNHGIVPTK DFGNREFALT LQNDAYLRYQ
SYPTADLFRK DILKMNPSRF EIGPVYSTNP RDRKTLRGGQ MKPVSKELVF DIDLTDYDDI
RTCCVKANIC AKCWAFVTMS IKVIDTALRE DFGFEHILWV YSGRRGAHAW VCDPRARNLP
DERRRAIAGY LEIVRGGSQS GKKVNIKRPL HPHIVRSLEL LKHDFARTTL GDQDTFESAE
QAERLLSLLP DKTLNESLRR KWDSSPDRAS TSKWADIDSL AKTGKSSTLN PATLRDAKQD
IVLEYTYPRL DAEVSKKMIH LLKSPFVIHP GTGRICVPID PRNAENFDPL SVPTVMSLLA
EIDEYDAKHP AGTAEADIPD VEGSAMNGSD IKGGRKVQDY EKTSLKPYID FFRSFIAALI
KEERAGKRER DDNGPAVKAD PMEF
//
