ID B6HEC3_PENRW Unreviewed; 544 AA.
AC B6HEC3;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Pc20g04990 protein {ECO:0000313|EMBL:CAP85828.1};
DE EC=1.1.99.18 {ECO:0000313|EMBL:CAP85828.1};
GN ORFNames=Pc20g04990 {ECO:0000313|EMBL:CAP85828.1}, PCH_Pc20g04990
GN {ECO:0000313|EMBL:CAP85828.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85828.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP85828.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; AM920435; CAP85828.1; -; Genomic_DNA.
DR RefSeq; XP_002563039.1; XM_002562993.1.
DR AlphaFoldDB; B6HEC3; -.
DR STRING; 500485.B6HEC3; -.
DR CAZy; AA3; Auxiliary Activities 3.
DR GeneID; 8314596; -.
DR KEGG; pcs:Pc20g04990; -.
DR VEuPathDB; FungiDB:PCH_Pc20g04990; -.
DR eggNOG; KOG1238; Eukaryota.
DR HOGENOM; CLU_011025_2_1_1; -.
DR OMA; LDVWNQY; -.
DR OrthoDB; 52047at2759; -.
DR BioCyc; PCHR:PC20G04990-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c20.
DR GO; GO:0047735; F:cellobiose dehydrogenase (acceptor) activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR47190; DEHYDROGENASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR47190:SF5; PX DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 2.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Oxidoreductase {ECO:0000313|EMBL:CAP85828.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..544
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002843573"
FT DOMAIN 278..292
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 113
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 121..124
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 240
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 544 AA; 58321 MW; 87254B084222DAA3 CRC64;
MRIFQAGPLA IALSVFTGAA SASAFQNHTY DYIVVGGGPS GIISAEKFAQ AGKKVLLLER
GVGPTVATGN NETLTWDHSL TPIDLPGLSA NIGALDVWNQ YMCTDTAGNA ACVLGGGVTV
NYMVFVHPPA RDFDDKWPEG WKWKDVESAA DRLYKRNPGT TLPSADGKRY DQGLYNVLSK
FLSGLGWKSV DMIAEPNEKH QIYSYPSWNV QDQMRAGPVR TYLPAAAKLD NFHLALRTKV
IRLVRSGSQV TGVEVQTPSG RSQIITVAPH GRVVLAAGAL STPRLLWNSG IGGKAQIETA
KKSGVAVPPK AQWIDLPVGV GLKDHPIFPI TFNTNASFGL VDYEGVLNGT DSRDISLYRK
HSGVLTQGKH RLIFFTSEEI DGHTQYYQGS CAPTDEGVVT MTTYMTHGLT SSGVLGLDAS
GNTVIEKLPY LQTAADRKAA RTFIQKMVKD ITAPSTGFEL ETHTNVSAIL KAQTPGTHYV
SSAKMGTDDG RKNGTSVVDT NAKVYGVDNL FIVDASIHPD LPTGNIQTAV MVVAEAAAVK
ILSN
//
