ID B6HGT0_PENRW Unreviewed; 315 AA.
AC B6HGT0;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Pc20g03670 protein {ECO:0000313|EMBL:CAP85696.1};
GN ORFNames=Pc20g03670 {ECO:0000313|EMBL:CAP85696.1}, PCH_Pc20g03670
GN {ECO:0000313|EMBL:CAP85696.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85696.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP85696.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O(in) = H2O(out); Xref=Rhea:RHEA:29667, ChEBI:CHEBI:15377;
CC Evidence={ECO:0000256|ARBA:ARBA00034651};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|RuleBase:RU000477}.
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DR EMBL; AM920435; CAP85696.1; -; Genomic_DNA.
DR RefSeq; XP_002562918.1; XM_002562872.1.
DR AlphaFoldDB; B6HGT0; -.
DR STRING; 500485.B6HGT0; -.
DR GeneID; 8309972; -.
DR KEGG; pcs:Pc20g03670; -.
DR VEuPathDB; FungiDB:PCH_Pc20g03670; -.
DR eggNOG; KOG0223; Eukaryota.
DR HOGENOM; CLU_020019_5_0_1; -.
DR OMA; LPRMVIY; -.
DR OrthoDB; 3236018at2759; -.
DR BioCyc; PCHR:PC20G03670-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c20.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR PANTHER; PTHR47002; AQUAPORIN-LIKE; 1.
DR PANTHER; PTHR47002:SF2; AQUAPORIN-LIKE; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
DR PROSITE; PS00221; MIP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000477};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 315 AA; 34092 MW; C0B2FE987FF97A5E CRC64;
MASFLPQTHE QPRPLEGQNG GIRRRFQVES TPFAGRIGAN QEFSVSPLEE AELLRKTPDA
APLVPWSQMI CPNQFIQLNI WKAAFVEGVV TCLLVYFTCF LAVGLGKMAG HLATGPVVPS
LIGGLLNTLT LPLFIFAAGP VSGGHVNPTI TMATFFARLS TFPRSILYIS FQLLGATVAG
YLLRGSFDTR SFVIPGCVID TSVVSVGSAF TIEVTTDFML IFLSFSVGLD PRQREVFGPA
LGPVFVGIIL GITSFGTGYS QVGYTGFGGN PARCFGAMVG SHFTSYHWIH WLGPIVASIL
HGIMYYFIPP YQYCV
//
