ID B6HGU5_PENRW Unreviewed; 1232 AA.
AC B6HGU5;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=Pc20g03820 protein {ECO:0000313|EMBL:CAP85711.1};
GN ORFNames=Pc20g03820 {ECO:0000313|EMBL:CAP85711.1}, PCH_Pc20g03820
GN {ECO:0000313|EMBL:CAP85711.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85711.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP85711.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM920435; CAP85711.1; -; Genomic_DNA.
DR RefSeq; XP_002562932.1; XM_002562886.1.
DR AlphaFoldDB; B6HGU5; -.
DR STRING; 500485.B6HGU5; -.
DR GeneID; 8309987; -.
DR KEGG; pcs:Pc20g03820; -.
DR VEuPathDB; FungiDB:PCH_Pc20g03820; -.
DR eggNOG; KOG2020; Eukaryota.
DR HOGENOM; CLU_003712_0_0_1; -.
DR OMA; IAKRSWG; -.
DR OrthoDB; 2721902at2759; -.
DR BioCyc; PCHR:PC20G03820-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c20.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045478; Exportin-5_C.
DR InterPro; IPR045065; XPO1/5.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF3; EXPORTIN-5; 1.
DR Pfam; PF19273; Exportin-5; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 106..182
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 328..1177
FT /note="Exportin-5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19273"
SQ SEQUENCE 1232 AA; 139612 MW; D4A767F189FCA7F9 CRC64;
MAAEELSEGG MADIIRALQL IHNPASSNDI RKEASQFVEN LKESDAAARN GFLLASRMEH
EPVVRYFGLT LLDHVLRQYN FTNPEEAKNL RMMILQLAEN VRPEDPAYFR NKISQLWTEA
AKKTWGLDWM DMDANLVQFW GASLVHKELV LAVLETLSED VFFREDTASS LRGGELNRSL
VEIFTPAGIV EQITGDKTTA TIPRCGQEGW LVRICEFLDN CVQNVSSSEQ ARDAATKALA
TLRSALSWSV YKGVIASQVV PSIFRALPCQ DDQVLLSAVE ALHALYGRNT IGSEDSQELV
CLIFQPVYLV VLQRLYEWSI VGPDDVDEPK YLISKKLSEM ISYIAGCLED DKFLVSTMDR
LNLPPFLQFM VNIMQHQSLT VSIPCLHLWS RLLQNSKISN LDFVVEQTPQ FLNICTQRLL
RWESLPTESE DPTVQFLVED IDTVPERHAF VGNYRRYCSS IIETITFKRP QEAVREILAR
VDTNLDNLYN GVQPFSMATF SKSSIPLMRA DAQFAVVEAV IKGYNKWISA HGKAPQRDES
KRMELEHAVE NWASTLMQKS FEDPVLKQRV IKLVVDISSK ALDNHQGFAL KVLEHILMSR
LPDRSEYPLY SEAVKELHGL ASSELRRLAM RYADYFYTFY DLLEPKIKEI TLANRIDDKL
QMELTSILLI IMQRAINADP YLRQNRLASF LQPIQEAWQD DQFRHSSSTF PGFCNMLGLE
NVGPYMQSKE AQKLADWSEV ALDNEGRLVQ EEMTRKFQLL PLRGTKTMLA VSTDRVKKSS
PAYATACQMW HELIPIILPT LLQLVRNAHA FHNPANWNMV EGMQPVVERI LTDRFWQAGI
SIGSRDEFYA RITSSKSTLE GFASSVRGKV RAVREACYSM LFSMSRMREH FYGFAELPGP
LSEALFVDSP HLSSHQFSVL LNISRCLIDD CPVQFRSQFL PPMLSTLFTN IDRKVTTEWE
IIEQRRNGIS DGDLTTEMKS ESVLRQLTYS AVIMVASLFD PQRGDPDGTE SDPTAPQPTP
NLSDSIRHFV LSSPQIFEPV MLFCTHALRM RDTRSGSIIT RVIRSILQDF APTNDTPDTP
TIATIREFIC TDVLTACISS VHESYFVDMQ KDLAQLIASI WCLYGFCSET PRAVFLSLPG
ISAEKVASTE SALHQTTSPR QQRALVLELL EPLRGISVAE QGKILGSREE RRKARSALQE
RYMTNEMDTQ QQNHRVDIND GPDLGGVADL FG
//
