ID B6HNW5_PENRW Unreviewed; 733 AA.
AC B6HNW5;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Pc21g22620 protein {ECO:0000313|EMBL:CAP97159.1};
GN ORFNames=Pc21g22620 {ECO:0000313|EMBL:CAP97159.1}, PCH_Pc21g22620
GN {ECO:0000313|EMBL:CAP97159.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP97159.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP97159.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the putative lipase ROG1 family.
CC {ECO:0000256|ARBA:ARBA00007920}.
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DR EMBL; AM920436; CAP97159.1; -; Genomic_DNA.
DR RefSeq; XP_002569230.1; XM_002569184.1.
DR AlphaFoldDB; B6HNW5; -.
DR GeneID; 8305331; -.
DR KEGG; pcs:Pc21g22620; -.
DR VEuPathDB; FungiDB:PCH_Pc21g22620; -.
DR eggNOG; KOG2029; Eukaryota.
DR HOGENOM; CLU_378156_0_0_1; -.
DR OMA; LLITEMP; -.
DR OrthoDB; 2239159at2759; -.
DR BioCyc; PCHR:PC21G22620-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c21.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007751; DUF676_lipase-like.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48182; PROTEIN SERAC1; 1.
DR PANTHER; PTHR48182:SF2; PROTEIN SERAC1; 1.
DR Pfam; PF05057; DUF676; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 141..264
FT /note="DUF676"
FT /evidence="ECO:0000259|Pfam:PF05057"
FT DOMAIN 497..629
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 733 AA; 82945 MW; EC50DF3B16AF7B55 CRC64;
MASEIRPLNA RNIHPCITMC FALSRSHVKS AMKPCYYPWV RLVTMYSPRF LPTYCLWTNI
RHIKAATQIV VSLLIMCLSL LITEMPVNYR PSIRCNLGAL HKNCAMAGEE TYGLTVLHDA
NFNFTTQEKN HSSSVVLFDL VAIHGLNGDA IDTWTHQKTR VMWLKDLLPE ALPNIRIMTF
GYNARFKNFT AQQDLRSISS KLLNELVDFR TTEEEKSRPI VFVCHSLGGI VAKKALLIGC
SEEQEQVQRS VYGVLFLGTP HNGSSLAVMG KLMANIVSAC SPMRPPRTLI GVLQKDSQAL
LEITEDFCKR RNKVKLISFY ELELTSIGPF LRKLIVKQQS ALLNVPHEIA IPQFADHRNI
VRFTSLQDRT FRPVLRRLQK LAQDFQGGST AQSTSAQELV LAIPFDITTL PCPSFCGRDD
VLEIMKTFFY GDPSESPTRR TFALCGLALH YVLQTRSQYK SGVALMNAAS VASLEADFDR
LHNLLKLGES KNKINSVRSW LSRAENSQWL LVFDNVDDLS SVPIRKYLPA VNWGHVIFTT
RDQGIIGEIA QEGHVLKPLT TEDAAQLLLE RSGVRHATDN EMEEARDIAD LLGSLPLALV
HAGAFLRSRH RTLGEYHQLY KTRRNELLRF STRLGDTNQA ILTAWEINFK QAEQESPAAT
NLLLLFSFLD QASIPELMLH RGSSPQKRNF SIHPLVQYCA VHRLPPSDVR RWRWQAILLV
CHAFPRNGYI EPL
//
