ID B6HVD4_PENRW Unreviewed; 609 AA.
AC B6HVD4;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Pc22g18900 protein {ECO:0000313|EMBL:CAP99178.1};
GN ORFNames=Pc22g18900 {ECO:0000313|EMBL:CAP99178.1}, PCH_Pc22g18900
GN {ECO:0000313|EMBL:CAP99178.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP99178.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP99178.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AM920437; CAP99178.1; -; Genomic_DNA.
DR RefSeq; XP_002565793.1; XM_002565747.1.
DR AlphaFoldDB; B6HVD4; -.
DR STRING; 500485.B6HVD4; -.
DR GeneID; 8313548; -.
DR KEGG; pcs:Pc22g18900; -.
DR VEuPathDB; FungiDB:PCH_Pc22g18900; -.
DR eggNOG; KOG2026; Eukaryota.
DR HOGENOM; CLU_016848_2_1_1; -.
DR OMA; NKFVAER; -.
DR OrthoDB; 719409at2759; -.
DR BioCyc; PCHR:PC22G18900-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c22.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000245; P:spliceosomal complex assembly; IEA:InterPro.
DR CDD; cd02669; Peptidase_C19M; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR033809; USP39.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001607; Znf_UBP.
DR PANTHER; PTHR21646:SF16; U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF02148; zf-UBP; 1.
DR SMART; SM00290; ZnF_UBP; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS50271; ZF_UBP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00502}.
FT DOMAIN 102..199
FT /note="UBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50271"
FT DOMAIN 224..598
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 1..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 67368 MW; E7ED5370DD8E7B89 CRC64;
MSKRQAELPL EQDFSGSPAS KKARVEDDND PGSINGAAPA SQKTGEEIRQ DDRNGVDILG
AAEIEGEELE EGEKDPSGLS DIDEDAPALS APKRQSAPME GYGDLYLDTI NREILDFDFE
KLCSVSLSNI NVYACLVCGK YFQGRGPKSH AYFHALEVGH HVFINIGTKK VYVLPEGYEV
NNKSLEDIKY VVDPHYTKNQ VVKLDKEVHD AWDLSGSRYR PGFVGMNNIK ANDYVNVVAQ
LLAHVLPIRN FFLLHEFPTP GTPEIILRFS TLVRKLWNPK AFRSHVSPHE LLQEVAVRSS
KRFTLTNQAD PVDFLSWFLN SLHLALGGSK KPSPTPTSVV HAAFQGRVRI ESQAITAHSD
TQNARLVFTE SGTINSQVTP FLILTLDLPP TPLFQSANRE SSIPQVPLTT LLNKYNGYTA
SEKLAHRVRH RLLHPLPPYL FFHIKRFSKN RFVSERNPTI VTFPSPHGLD MSPYVEPNPN
ICSPSEPILY DLVANIILDP AIAAPGAMDD AVDKGVNAAS GAGGSSSGAG GGSEKVSWLV
QLHDKAMEAE NTRAKNGGST EKQQRGPEWL EIQDLFVKRA ESETLFTREG YLMVWERRKV
PGNKGKGRA
//
