ID B6HVP9_PENRW Unreviewed; 1279 AA.
AC B6HVP9;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Pc22g19160 protein {ECO:0000313|EMBL:CAP99204.1};
GN ORFNames=Pc22g19160 {ECO:0000313|EMBL:CAP99204.1}, PCH_Pc22g19160
GN {ECO:0000313|EMBL:CAP99204.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP99204.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP99204.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR EMBL; AM920437; CAP99204.1; -; Genomic_DNA.
DR RefSeq; XP_002565819.1; XM_002565773.1.
DR AlphaFoldDB; B6HVP9; -.
DR STRING; 500485.B6HVP9; -.
DR GeneID; 8315919; -.
DR KEGG; pcs:Pc22g19160; -.
DR VEuPathDB; FungiDB:PCH_Pc22g19160; -.
DR eggNOG; KOG0401; Eukaryota.
DR HOGENOM; CLU_003998_0_0_1; -.
DR OMA; PRGGPNM; -.
DR OrthoDB; 92033at2759; -.
DR BioCyc; PCHR:PC22G19160-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c22.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 1.20.970.30; eIF4G, eIF4E-binding domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR022745; eIF4G1_eIF4E-bd.
DR InterPro; IPR036211; eIF4G_eIF4E-bd_sf.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF9; EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED; 1.
DR Pfam; PF12152; eIF_4G1; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101489; Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT DOMAIN 847..1086
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 1..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 814..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1110..1279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..351
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..793
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1167..1193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1241..1257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1279 AA; 137849 MW; 993599AD71948DAB CRC64;
MRSIQASLAH GAQHLRRESS QSTHSDMSNH MGNGPGRSGY QGGRGRGYSQ PGYQGQQMPY
SPNPGFRQTP NQPRGGPNMG PQFQNQGRPL APYPNSPHQA NRSPALANVN PTTPQMNQVP
MAHPQMPQQP YGYGQHMGPQ AVRSPPSRSS QDSWRRPQRN LSSSWRRKDN PPYSPEYPVD
LAPESGHFEQ FLTMVKFQQS FPNAYDPNYA GYYNPNGGYY MGPPSPQPRA AGMPYNPQYM
GQQFPNPMPQ ATPLSRTPSQ VSTDRPGSSL GHGPAPTGPA APSHTHTGSR ASNSPAPKPH
FIIPSAKKSP IIIKDPNSGS VKTFEKNPAS PARATPSPVK FTPPPTSTPP PRTASASEHT
RTESKANATK TDEEKKQELK DAVRLKIQQD EAAQKQRLAD EASRKTTEAV STDAKKDDTE
AARAAIEDLS IKDKAEEPKK VEAAEESKET ATPAEEPKKA PAPAPAPVDD DEIDFDAIER
EMAEIEAKER AAEEDYNRAK QAKKEEAERK EREELENYEA NMKKAEAEAE AREIAREKAR
AGGEAVQDDT KDAFAALKKG GYGATESSTP GDSGAATPVS SDMGPPAKPA SAIPKKPAGL
KLDTPKPTEP QQATAGMKSL QNAKFLEDLG KVTYPASITP PDATMNAAAP EGRKFHYDRN
FLLQFQAAFK DKISVDWDAR LRDTVGDPTD TSRPQSARTP SGMGSRAGSR SGPMNTAFPM
GNFTGRPGQL PPMGGGPMGS RNASAPFGFP RGAGGMGPIG NIRQHSAGVP PRGNSSKGPR
TDSRPKKQGG RQDEAANKSM PLTAGMELKA IQTSASGWKP RSVGQAAGAG AGPAPGGEAY
LAPDVVQRKV KAALNKMTPE NFDRISGQIL AIVSQSKDET DGRTLRQVIQ LTFEKATDEA
HWAPMYAKFC KSMLESMSPE IKDENIRDRN GTVVAGGSLF RKYLLNRCQE EFERGWKTNL
PAKPEGTTEE IAMMSDEYYI AAAAKRRGLG LVKFIGELYK LGMLTERIMH ECVKKLVDYE
GVPDEAEVES LTSLLRTIGA SLDASEKGPA MMDAYFVRIH MMMETPNLPS RLRFMLLDII
DLRAARWNSK DADKGPQTIV EIREAAARAA QAAEAERQRQ SSNRGGGGRI PMGRGDARGF
GYGNQPPPPD YASSKVGSDD LRRLRATRNT NQPMSFGPSS LLGSRTNSGR KNLGPGGSLV
RGSDDSASSS RTGTPTGSKK EDNSSMNAFS ALAALEDRDN LATSPPSNPT SPMLTKSQPA
AAERRPSKTP SVKDGEAPA
//
